Synthesis and antiviral activity of indole and benzofuran sulfides
Abstract New arbidol analogs of the indole and benzofuran series were synthesized. The phenyl in them was replaced with substituted phenyl or separated from the sulfide bridge by a methylene group. The antivirus activity of the synthesized compounds was studied using enzyme-linked immunoassay and a murine influenza-induced pneumonia model. Both 5-hydroxyindole and 5-hydroxybenzofuran derivatives were found to have antiviral activity..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1995 |
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| Erschienen: |
1995 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:29 |
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| Enthalten in: |
Pharmaceutical chemistry journal - 29(1995), 1 vom: Jan., Seite 57-59 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zotova, S. A. [VerfasserIn] |
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| Links: |
Volltext [lizenzpflichtig] |
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| Themen: |
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| Anmerkungen: |
© Plenum Publishing Corporation 1995 |
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| doi: |
10.1007/BF02219467 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC2038526281 |
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| 100 | 1 | |a Zotova, S. A. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Synthesis and antiviral activity of indole and benzofuran sulfides |
| 264 | 1 | |c 1995 | |
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| 500 | |a © Plenum Publishing Corporation 1995 | ||
| 520 | |a Abstract New arbidol analogs of the indole and benzofuran series were synthesized. The phenyl in them was replaced with substituted phenyl or separated from the sulfide bridge by a methylene group. The antivirus activity of the synthesized compounds was studied using enzyme-linked immunoassay and a murine influenza-induced pneumonia model. Both 5-hydroxyindole and 5-hydroxybenzofuran derivatives were found to have antiviral activity. | ||
| 650 | 4 | |a Methylene | |
| 650 | 4 | |a Sulfide | |
| 650 | 4 | |a Organic Chemistry | |
| 650 | 4 | |a Pneumonia | |
| 650 | 4 | |a Phenyl | |
| 700 | 1 | |a Korneeva, T. M. |4 aut | |
| 700 | 1 | |a Shvedov, V. I. |4 aut | |
| 700 | 1 | |a Fadeeva, N. I. |4 aut | |
| 700 | 1 | |a Leneva, I. A. |4 aut | |
| 700 | 1 | |a Fedyakina, I. T. |4 aut | |
| 700 | 1 | |a Khristova, M. L. |4 aut | |
| 700 | 1 | |a Nikolaeva, I. S. |4 aut | |
| 700 | 1 | |a Peters, V. V. |4 aut | |
| 700 | 1 | |a Gus'kova, T. A. |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Pharmaceutical chemistry journal |d Kluwer Academic Publishers-Plenum Publishers, 1967 |g 29(1995), 1 vom: Jan., Seite 57-59 |w (DE-627)130010669 |w (DE-600)418538-9 |w (DE-576)015555631 |x 0091-150X |7 nnns |
| 773 | 1 | 8 | |g volume:29 |g year:1995 |g number:1 |g month:01 |g pages:57-59 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/BF02219467 |z lizenzpflichtig |3 Volltext |
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