Graphene nanopores toward DNA sequencing: a review of experimental aspects

Abstract Nanopores for DNA sequencing have drawn much attention due to their potentials to achieve amplification-free, low-cost, and high-throughput analysis of nuclei acids. The material configuration and fabrication of the nanopore has become one important consideration in the nanopore based DNA sequencing research. Among various materials, the newly emerged graphene has brought more opportunities to the development of sequencing technology because of its unique structures and properties. This review mainly focuses on the experimental aspects of graphene nanopore research including the nanopore fabrication methods and processes. Meanwhile, the challenges in the present graphene nanopore research including hydrophobicity, translocation velocity and noise are also addressed and discussed..

Medienart:

Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:60

Enthalten in:

Science China / Chemistry - 60(2017), 6 vom: 27. Apr., Seite 721-729

Sprache:

Englisch

Beteiligte Personen:

Chen, Wei [VerfasserIn]
Liu, Guo-Chang [VerfasserIn]
Ouyang, Jun [VerfasserIn]
Gao, Meng-Juan [VerfasserIn]
Liu, Bo [VerfasserIn]
Zhao, Yuan-Di [VerfasserIn]

Links:

Volltext [lizenzpflichtig]

BKL:

35.00 / Chemie: Allgemeines / Chemie: Allgemeines

Themen:

DNA sequencing
Graphene nanopore
Nanopore fabrication

Anmerkungen:

© Science China Press and Springer-Verlag Berlin Heidelberg 2017

doi:

10.1007/s11426-016-9016-5

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC2035812860