Radiographic involvement of metacarpophalangeal and radiocarpal joints in hand osteoarthritis
Abstract To evaluate, by means of a longitudinal study, radiographic involvement of metacarpophalangeal and radio-carpal joints in hand osteoarthritis, its relationship with erosive disease and its progression, 368 patients with hand osteoarthritis were enrolled. All patients underwent hand X-rays. On the basis of the presence of central erosions in interphalangeal joints, patients were divided into three groups: 0—no central erosions, 1—one joint with central erosion, and 2—two or more joints with central erosions. A longitudinal study on 44 patients and nine normal controls, whose X-rays were available after 3.9 years, was performed. The radiological involvement of metacarpophalangeal and radio-carpal joints was evaluated using Kellgren-Lawrence and OARSI scores. Low number of joints showed Kellgren-Lawrence values ≥2 group 0, 42/1290 (3.3%); group 1, 10/410 (2.4%); and group 2, 36/1980 (1.8%). Low score values were obtained for all radiographic items. Only metacarpophalangeal joint space narrowing score showed significant increase from groups 0 to 2. Subsequent adjustment for age, gender, and BMI did not confirm the statistical significance. Marginal erosions were rarely found (6.7% of joints). Metacarpophalangeal and radio-carpal radiographic per patient scores significantly worsened at follow-up, but no significant increase in joints with Kellgren-Lawrence score ≥2 was found. In normal controls, no significant radiographic worsening was found. Only a minority of metacarpophalangeal joints shows a Kellgren-Lawrence value ≥2. Metacarpophalangeal and to lesser extent radiocarpal joints had significant worsening at follow-up. Metacarpophalangeal joint involvement in hand osteoarthritis is mild but progressive. Radiocarpal involvement is negligible..
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2017 |
|---|---|
| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
|---|---|
| Enthalten in: |
Clinical rheumatology - 36(2017), 5 vom: 04. Feb., Seite 1077-1082 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Addimanda, Olga [VerfasserIn] |
|---|
| Links: |
Volltext [lizenzpflichtig] |
|---|
| Themen: |
|---|
| Anmerkungen: |
© International League of Associations for Rheumatology (ILAR) 2017 |
|---|
| doi: |
10.1007/s10067-017-3565-1 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
OLC2025711913 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | OLC2025711913 | ||
| 003 | DE-627 | ||
| 005 | 20230514094311.0 | ||
| 007 | tu | ||
| 008 | 200819s2017 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s10067-017-3565-1 |2 doi | |
| 035 | |a (DE-627)OLC2025711913 | ||
| 035 | |a (DE-He213)s10067-017-3565-1-p | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 610 |q VZ |
| 100 | 1 | |a Addimanda, Olga |e verfasserin |0 (orcid)0000-0002-1267-5764 |4 aut | |
| 245 | 1 | 0 | |a Radiographic involvement of metacarpophalangeal and radiocarpal joints in hand osteoarthritis |
| 264 | 1 | |c 2017 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a © International League of Associations for Rheumatology (ILAR) 2017 | ||
| 520 | |a Abstract To evaluate, by means of a longitudinal study, radiographic involvement of metacarpophalangeal and radio-carpal joints in hand osteoarthritis, its relationship with erosive disease and its progression, 368 patients with hand osteoarthritis were enrolled. All patients underwent hand X-rays. On the basis of the presence of central erosions in interphalangeal joints, patients were divided into three groups: 0—no central erosions, 1—one joint with central erosion, and 2—two or more joints with central erosions. A longitudinal study on 44 patients and nine normal controls, whose X-rays were available after 3.9 years, was performed. The radiological involvement of metacarpophalangeal and radio-carpal joints was evaluated using Kellgren-Lawrence and OARSI scores. Low number of joints showed Kellgren-Lawrence values ≥2 group 0, 42/1290 (3.3%); group 1, 10/410 (2.4%); and group 2, 36/1980 (1.8%). Low score values were obtained for all radiographic items. Only metacarpophalangeal joint space narrowing score showed significant increase from groups 0 to 2. Subsequent adjustment for age, gender, and BMI did not confirm the statistical significance. Marginal erosions were rarely found (6.7% of joints). Metacarpophalangeal and radio-carpal radiographic per patient scores significantly worsened at follow-up, but no significant increase in joints with Kellgren-Lawrence score ≥2 was found. In normal controls, no significant radiographic worsening was found. Only a minority of metacarpophalangeal joints shows a Kellgren-Lawrence value ≥2. Metacarpophalangeal and to lesser extent radiocarpal joints had significant worsening at follow-up. Metacarpophalangeal joint involvement in hand osteoarthritis is mild but progressive. Radiocarpal involvement is negligible. | ||
| 650 | 4 | |a Imaging–radiology | |
| 650 | 4 | |a OA | |
| 700 | 1 | |a Cavallari, Carlotta |4 aut | |
| 700 | 1 | |a Pignotti, Elettra |4 aut | |
| 700 | 1 | |a Pulsatelli, Lia |4 aut | |
| 700 | 1 | |a Mancarella, Luana |4 aut | |
| 700 | 1 | |a Ramonda, Roberta |4 aut | |
| 700 | 1 | |a Fioravanti, Antonella |4 aut | |
| 700 | 1 | |a Meliconi, Riccardo |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Clinical rheumatology |d Springer London, 1982 |g 36(2017), 5 vom: 04. Feb., Seite 1077-1082 |w (DE-627)167914960 |w (DE-600)604755-5 |w (DE-576)024860131 |x 0770-3198 |7 nnns |
| 773 | 1 | 8 | |g volume:36 |g year:2017 |g number:5 |g day:04 |g month:02 |g pages:1077-1082 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/s10067-017-3565-1 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a SSG-OLC-DE-84 | ||
| 912 | |a GBV_ILN_2018 | ||
| 912 | |a GBV_ILN_4012 | ||
| 912 | |a GBV_ILN_4219 | ||
| 912 | |a GBV_ILN_4277 | ||
| 951 | |a AR | ||
| 952 | |d 36 |j 2017 |e 5 |b 04 |c 02 |h 1077-1082 | ||