Comparison of the effects of model-based iterative reconstruction and filtered back projection algorithms on software measurements in pulmonary subsolid nodules

Objectives To evaluate the differences between filtered back projection (FBP) and model-based iterative reconstruction (MBIR) algorithms on semi-automatic measurements in subsolid nodules (SSNs). Methods Unenhanced CT scans of 73 SSNs obtained using the same protocol and reconstructed with both FBP and MBIR algorithms were evaluated by two radiologists. Diameter, mean attenuation, mass and volume of whole nodules and their solid components were measured. Intra- and interobserver variability and differences between FBP and MBIR were then evaluated using Bland-Altman method and Wilcoxon tests. Results Longest diameter, volume and mass of nodules and those of their solid components were significantly higher using MBIR (p<0.05) with mean differences of 1.1% (limits of agreement, -6.4 to 8.5%), 3.2% (-20.9 to 27.3%) and 2.9% (-16.9 to 22.7%) and 3.2% (-20.5 to 27%), 6.3% (-51.9 to 64.6%), 6.6% (-50.1 to 63.3%), respectively. The limits of agreement between FBP and MBIR were within the range of intra- and interobserver variability for both algorithms with respect to the diameter, volume and mass of nodules and their solid components. There were no significant differences in intra- or interobserver variability between FBP and MBIR (p>0.05). Conclusion Semi-automatic measurements of SSNs significantly differed between FBP and MBIR; however, the differences were within the range of measurement variability. Key points * Intra- and interobserver reproducibility of measurements did not differ between FBP and MBIR. * Differences in SSNs' semi-automatic measurement induced by reconstruction algorithms were not clinically significant. * Semi-automatic measurement may be conducted regardless of reconstruction algorithm. * SSNs' semi-automated classification agreement (pure vs. part-solid) did not significantly differ between algorithms..

Medienart:

Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

European radiology - 27(2017), 8, Seite 3266

Sprache:

Englisch

Beteiligte Personen:

Cohen, Julien G [VerfasserIn]
Kim, Hyungjin [Sonstige Person]
Park, Su Bin [Sonstige Person]
van Ginneken, Bram [Sonstige Person]
Ferretti, Gilbert R [Sonstige Person]
Lee, Chang Hyun [Sonstige Person]
Goo, Jin Mo [Sonstige Person]
Park, Chang Min [Sonstige Person]

Links:

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Themen:

Algorithms
Automation
Classification
Computer aided tomography
Iterative methods
Lung nodules
Nodules
Reconstruction
Reproducibility
Test procedures
Variability

doi:

10.1007/s00330-016-4716-5

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC1996316745