Neutrophil‐To‐Lymphocyte Ratio: An Emerging Marker Predicting Prognosis in Elderly Adults with Community‐Acquired Pneumonia
To explore the performance of the neutrophil-to-lymphocyte ratio (NLR), an index of systemic inflammation that predicts prognosis of several diseases, in a cohort of elderly adults with community-acquired pneumonia (CAP). Unit of Internal Medicine, University of Catania, Catania, Italy. Elderly adults admitted for CAP (N = 195). Clinical diagnosis of CAP was defined as the presence of a new infiltrate on plain chest radiography or chest computed tomography associated with one or more suggestive clinical features such as dyspnea, hypo- or hyperthermia, cough, sputum production, tachypnea (respiration rate >20 breaths per minute), altered breath sounds on physical examination, hypoxemia (partial pressure of oxygen 10,000/I1/4L). Clinical examination, traditional tests such as Pneumonia Severity Index (PSI); Confusion, Urea, Respiratory rate, Blood pressure, aged 65 and older (CURB-65), and NLR were evaluated at admission. The accuracy and predictive value for 30-day mortality of traditional scores and NLR were compared. These results would encourage early discharge of individuals with a NLR of less than 11.12, short-term in-hospital care for those with a NLR between 11.12 and 13.4, middle-term hospitalization for those with a NLR between 13.4 and 28.3, and admission to a respiratory intensive care unit for those with a NLR greater than 28.3..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:65 |
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| Enthalten in: |
Journal of the American Geriatrics Society - 65(2017), 8, Seite 1796-1801 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cataudella, Emanuela [VerfasserIn] |
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| Links: |
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| doi: |
10.1111/jgs.14894 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 245 | 1 | 0 | |a Neutrophil‐To‐Lymphocyte Ratio: An Emerging Marker Predicting Prognosis in Elderly Adults with Community‐Acquired Pneumonia |
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| 520 | |a To explore the performance of the neutrophil-to-lymphocyte ratio (NLR), an index of systemic inflammation that predicts prognosis of several diseases, in a cohort of elderly adults with community-acquired pneumonia (CAP). Unit of Internal Medicine, University of Catania, Catania, Italy. Elderly adults admitted for CAP (N = 195). Clinical diagnosis of CAP was defined as the presence of a new infiltrate on plain chest radiography or chest computed tomography associated with one or more suggestive clinical features such as dyspnea, hypo- or hyperthermia, cough, sputum production, tachypnea (respiration rate >20 breaths per minute), altered breath sounds on physical examination, hypoxemia (partial pressure of oxygen 10,000/I1/4L). Clinical examination, traditional tests such as Pneumonia Severity Index (PSI); Confusion, Urea, Respiratory rate, Blood pressure, aged 65 and older (CURB-65), and NLR were evaluated at admission. The accuracy and predictive value for 30-day mortality of traditional scores and NLR were compared. These results would encourage early discharge of individuals with a NLR of less than 11.12, short-term in-hospital care for those with a NLR between 11.12 and 13.4, middle-term hospitalization for those with a NLR between 13.4 and 28.3, and admission to a respiratory intensive care unit for those with a NLR greater than 28.3. | ||
| 540 | |a Nutzungsrecht: 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics Society | ||
| 540 | |a © COPYRIGHT 2017 Blackwell Publishers Ltd. | ||
| 650 | 4 | |a community‐acquired pneumonia | |
| 650 | 4 | |a elderly adults | |
| 650 | 4 | |a NLR | |
| 650 | 4 | |a CAP | |
| 650 | 4 | |a prognostic score | |
| 650 | 4 | |a Aged | |
| 650 | 4 | |a Medicine, Experimental | |
| 650 | 4 | |a Blood cell count | |
| 650 | 4 | |a Medical research | |
| 650 | 4 | |a Mortality | |
| 650 | 4 | |a Hyperthermia | |
| 650 | 4 | |a Hypoxemia | |
| 650 | 4 | |a Respiration | |
| 650 | 4 | |a Prognosis | |
| 650 | 4 | |a Cough | |
| 650 | 4 | |a Urea | |
| 650 | 4 | |a Chest | |
| 650 | 4 | |a Blood pressure | |
| 650 | 4 | |a Blood | |
| 650 | 4 | |a Leukocytosis | |
| 650 | 4 | |a Neutrophils | |
| 650 | 4 | |a Computed tomography | |
| 650 | 4 | |a Geriatrics | |
| 650 | 4 | |a Radiography | |
| 650 | 4 | |a Sputum | |
| 650 | 4 | |a Dyspnea | |
| 650 | 4 | |a Pneumonia | |
| 650 | 4 | |a C-reactive protein | |
| 700 | 1 | |a Giraffa, Chiara M |4 oth | |
| 700 | 1 | |a Di Marca, Salvatore |4 oth | |
| 700 | 1 | |a Pulvirenti, Alfredo |4 oth | |
| 700 | 1 | |a Alaimo, Salvatore |4 oth | |
| 700 | 1 | |a Pisano, Marcella |4 oth | |
| 700 | 1 | |a Terranova, Valentina |4 oth | |
| 700 | 1 | |a Corriere, Thea |4 oth | |
| 700 | 1 | |a Ronsisvalle, Maria L |4 oth | |
| 700 | 1 | |a Di Quattro, Rosario |4 oth | |
| 700 | 1 | |a Stancanelli, Benedetta |4 oth | |
| 700 | 1 | |a Giordano, Mauro |4 oth | |
| 700 | 1 | |a Vancheri, Carlo |4 oth | |
| 700 | 1 | |a Malatino, Lorenzo |4 oth | |
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