Osimertinib in EGFR T790M-Positive Lung Cancer
To the Editor: Mok et al. (Feb. 16 issue)1 report on the use of osimertinib in patients in the AURA3 trial who had lung cancer and a p.Thr790Met point mutation (T790M) in the gene encoding epidermal growth factor receptor (EGFR). In their article, the descriptions of pulmonary toxic effects are confusing because of a mixed use of terms, including interstitial lung disease, interstitial lung disease-like adverse events, and pneumonitis..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:376 |
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| Enthalten in: |
The New England journal of medicine - 376(2017), 20, Seite 1992 |
| Sprache: |
Englisch |
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| Links: |
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| BKL: | |
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| Themen: |
Cancer therapies |
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| 520 | |a To the Editor: Mok et al. (Feb. 16 issue)1 report on the use of osimertinib in patients in the AURA3 trial who had lung cancer and a p.Thr790Met point mutation (T790M) in the gene encoding epidermal growth factor receptor (EGFR). In their article, the descriptions of pulmonary toxic effects are confusing because of a mixed use of terms, including interstitial lung disease, interstitial lung disease-like adverse events, and pneumonitis. | ||
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