This Week in the Journal
Survival and Neurodevelopment among Periviable Infants This study assessed survival and neurodevelopmental outcomes among infants born at 22 to 24 weeks of gestation, as measured at 18 to 22 months of corrected age, and showed that the rate of survival without neurodevelopmental impairment increased between 2000 and 2011. see (Original Article, N Engl J Med 2017;376:617-628) Osimertinib in EGFR-Mutated Lung Cancer In a randomized trial involving patients with non-small-cell lung cancer with mutant EGFR (T790M) in whom a tyrosine kinase inhibitor had failed, osimertinib was associated with significantly longer progression-free survival than platinum therapy plus pemetrexed. see (Original Article, N Engl J Med 2017;376:629-640) Bariatric Surgery or Medical Therapy for Type 2 Diabetes Five-year data showed that among patients with type 2 diabetes and a BMI of 27 to 43, bariatric surgery plus intensive medical therapy was more effective than intensive medical therapy alone in decreasing or resolving hyperglycemia, even among those with a BMI of less than 35. see (Original Article, N Engl J Med 2017;376:-) Baricitinib in Rheumatoid Arthritis In a phase 3 randomized trial of 1307 patients with rheumatoid arthritis receiving background methotrexate, the oral JAK1 and JAK2 inhibitor baricitinib showed superior efficacy to placebo and to the anti-tumor necrosis factor [alpha] monoclonal antibody adalimumab. see (Original Article, N Engl J Med 2017;376:652-662) Opioid Prescribing and Risk of Long-Term Use In this analysis involving Medicare patients seen in emergency departments, rates of opioid prescribing varied widely among emergency physicians..
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Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:376 |
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| Enthalten in: |
The New England journal of medicine - 376(2017), 7, Seite 616 |
| Sprache: |
Englisch |
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| Themen: |
Clinical medicine |
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| 520 | |a Survival and Neurodevelopment among Periviable Infants This study assessed survival and neurodevelopmental outcomes among infants born at 22 to 24 weeks of gestation, as measured at 18 to 22 months of corrected age, and showed that the rate of survival without neurodevelopmental impairment increased between 2000 and 2011. see (Original Article, N Engl J Med 2017;376:617-628) Osimertinib in EGFR-Mutated Lung Cancer In a randomized trial involving patients with non-small-cell lung cancer with mutant EGFR (T790M) in whom a tyrosine kinase inhibitor had failed, osimertinib was associated with significantly longer progression-free survival than platinum therapy plus pemetrexed. see (Original Article, N Engl J Med 2017;376:629-640) Bariatric Surgery or Medical Therapy for Type 2 Diabetes Five-year data showed that among patients with type 2 diabetes and a BMI of 27 to 43, bariatric surgery plus intensive medical therapy was more effective than intensive medical therapy alone in decreasing or resolving hyperglycemia, even among those with a BMI of less than 35. see (Original Article, N Engl J Med 2017;376:-) Baricitinib in Rheumatoid Arthritis In a phase 3 randomized trial of 1307 patients with rheumatoid arthritis receiving background methotrexate, the oral JAK1 and JAK2 inhibitor baricitinib showed superior efficacy to placebo and to the anti-tumor necrosis factor [alpha] monoclonal antibody adalimumab. see (Original Article, N Engl J Med 2017;376:652-662) Opioid Prescribing and Risk of Long-Term Use In this analysis involving Medicare patients seen in emergency departments, rates of opioid prescribing varied widely among emergency physicians. | ||
| 650 | 4 | |a Rheumatoid arthritis | |
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