Two-dimensional shear-wave elastography: a new method comparable to acoustic radiation force impulse imaging?

OBJECTIVESTwo-dimensional shear-wave elastography (2D-SWE) is an ultrasound-based technique for the noninvasive assessment of tissue stiffness. In contrast to the well-established point-shear-wave elastography (pSWE) method acoustic radiation force impulse imaging, there is little evidence on the performance and usefulness of 2D-SWE in the assessment of liver stiffness. Thus, the aim of our study was to compare 2D-SWE versus pSWE. MATERIALS AND METHODS2D-SWE and pSWE were performed in 20 cirrhotic patients, 20 healthy individuals and an elasticity phantom. Stiffness values, examination time and number of measurements were compared. For 2D-SWE, the influence of size of the region of interest (ROI) was assessed. RESULTSElastography values in healthy individuals were slightly higher for 2D-SWE versus pSWE (1.4 m/s, range1.21–1.68 vs. 1.23 m/s, range1.07–1.39). In cirrhotic patients, there were no significant differences (3.06 m/s, range1.83–5.35 vs. 3 m/s, range1.67–4.37 m/s). Examination times were significantly longer for 2D-SWE in both patient groups (mean values for healthy/cirrhotic patients129.6/157.1 vs. 75/71.6 s). For 2D-SWE, variation of ROI size (5, 10, 20 mm) produced comparable results. After eight measurements, 90% of cirrhotic patients showed less than 5% of deviation from the results after the gold standard of 10 measurements; for healthy individuals, this was observed after six measurements. CONCLUSION2D-SWE seems to be comparable to pSWE (acoustic radiation force impulse-imaging) in cirrhotic patients, with slightly higher values in healthy individuals. 2D-SWE measurements require considerably more time. For 2D-SWE, ROI size seems to be of minor importance; multiple measurements should be obtained as single measurements differ. These preliminary results should be confirmed in larger patient collectives with histology as the reference standard..

Medienart:	Artikel

Erscheinungsjahr:	2017
Erschienen:	2017

Enthalten in:	Zur Gesamtaufnahme - year:2017
Enthalten in:	European journal of gastroenterology & hepatology - (2017), Seite 1

Sprache:	Englisch

Beteiligte Personen:	Schellhaas, Barbara [VerfasserIn] Strobel, Deike [Sonstige Person] Wildner, Dane [Sonstige Person] Goertz, Ruediger S [Sonstige Person] Neurath, Markus F [Sonstige Person] Pfeifer, Lukas [Sonstige Person]

Links:	Volltext

BKL:	44.87

doi:	10.1097/MEG.0000000000000846

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PPN (Katalog-ID):	OLC1989138292