The Role of Emerging Biomarkers in Unraveling the Complex Biology Underlying Associations between HDL Cholesterol and Cardiovascular Diseases
treatment of psoriasis with antiinflammatory therapy using the tumor necrosis factor inhibitor adalimumab resulted in decreases in GlycA and a reduction in vascular disease severity, with GlycA maintaining a strong relationship with psoriasis and vascular disease following therapy, suggesting a robust relationship with cardiovascular risk in chronic inflammatory states. Consistent with previous studies, GlycA was found to be positively associated with the presence and extent of coronary artery disease (odds ratio 1.07; 95% CI, 1.02-1.13) and with all-cause mortality (hazard ratio 1.34; 95% CI, 1.29-1.39) in models fully adjusted for cardiovascular risk factors..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:63 |
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| Enthalten in: |
Clinical chemistry - 63(2017), 1, Seite 27-29 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Small, Aeron M [VerfasserIn] |
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| Links: |
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| doi: |
10.1373/clinchem.2016.267922 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC1987799089 |
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| 245 | 1 | 4 | |a The Role of Emerging Biomarkers in Unraveling the Complex Biology Underlying Associations between HDL Cholesterol and Cardiovascular Diseases |
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| 520 | |a treatment of psoriasis with antiinflammatory therapy using the tumor necrosis factor inhibitor adalimumab resulted in decreases in GlycA and a reduction in vascular disease severity, with GlycA maintaining a strong relationship with psoriasis and vascular disease following therapy, suggesting a robust relationship with cardiovascular risk in chronic inflammatory states. Consistent with previous studies, GlycA was found to be positively associated with the presence and extent of coronary artery disease (odds ratio 1.07; 95% CI, 1.02-1.13) and with all-cause mortality (hazard ratio 1.34; 95% CI, 1.29-1.39) in models fully adjusted for cardiovascular risk factors. | ||
| 650 | 4 | |a Mortality | |
| 650 | 4 | |a Atoms & subatomic particles | |
| 650 | 4 | |a Nuclear magnetic resonance--NMR | |
| 650 | 4 | |a Studies | |
| 650 | 4 | |a Biomarkers | |
| 650 | 4 | |a Cholesterol | |
| 650 | 4 | |a Inflammation | |
| 650 | 4 | |a Cardiovascular disease | |
| 650 | 4 | |a Psoriasis | |
| 650 | 4 | |a Risk factors | |
| 650 | 4 | |a Tomography | |
| 650 | 4 | |a Proteins | |
| 650 | 4 | |a Health risk assessment | |
| 650 | 4 | |a Metabolism | |
| 650 | 4 | |a Biology | |
| 700 | 1 | |a Mehta, Nehal N |4 oth | |
| 700 | 1 | |a Rader, Daniel J |4 oth | |
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