Hypoglycemia, frailty and dementia in older people with diabetes: Reciprocal relations and clinical implications
The relationships between hypoglycemia, frailty and dementia appear to be reciprocal and can lead to a vicious circle. Frailty appears to be a crucial factor increasing the risk for both hypoglycemia and dementia, initiating the reciprocal relationships. Weight loss is likely to be the underlying risk factor for frailty. Many frail older people with diabetes seem to have unnecessarily tight glycemic control, being treated with hypoglycemic medications that likely increase the risk of hypoglycemia. As patients get older with significant weight loss their glycemic targets should be reviewed, and reduction or even withdrawal of their hypoglycemic medications should be considered..
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2016 |
|---|---|
| Erschienen: |
2016 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
|---|---|
| Enthalten in: |
Journal of diabetes and its complications - 30(2016), 8, Seite 1548-1554 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Abdelhafiz, Ahmed H [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Age |
|---|
| doi: |
10.1016/j.jdiacomp.2016.07.027 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
OLC1985518643 |
|---|
| LEADER | 01000caa a2200265 4500 | ||
|---|---|---|---|
| 001 | OLC1985518643 | ||
| 003 | DE-627 | ||
| 005 | 20230714231021.0 | ||
| 007 | tu | ||
| 008 | 161202s2016 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.jdiacomp.2016.07.027 |2 doi | |
| 028 | 5 | 2 | |a PQ20170301 |
| 035 | |a (DE-627)OLC1985518643 | ||
| 035 | |a (DE-599)GBVOLC1985518643 | ||
| 035 | |a (PRQ)c1288-95229e170ca07a2856ef5e72e8990fd5308c19fb9cc3db9d522317c4e83e40420 | ||
| 035 | |a (KEY)0146708520160000030000801548hypoglycemiafrailtyanddementiainolderpeoplewithdia | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 610 |q DNB |
| 100 | 1 | |a Abdelhafiz, Ahmed H |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Hypoglycemia, frailty and dementia in older people with diabetes: Reciprocal relations and clinical implications |
| 264 | 1 | |c 2016 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 520 | |a The relationships between hypoglycemia, frailty and dementia appear to be reciprocal and can lead to a vicious circle. Frailty appears to be a crucial factor increasing the risk for both hypoglycemia and dementia, initiating the reciprocal relationships. Weight loss is likely to be the underlying risk factor for frailty. Many frail older people with diabetes seem to have unnecessarily tight glycemic control, being treated with hypoglycemic medications that likely increase the risk of hypoglycemia. As patients get older with significant weight loss their glycemic targets should be reviewed, and reduction or even withdrawal of their hypoglycemic medications should be considered. | ||
| 650 | 4 | |a Age | |
| 650 | 4 | |a Aging | |
| 650 | 4 | |a Frailty | |
| 650 | 4 | |a Patients | |
| 650 | 4 | |a Hypoglycemia | |
| 650 | 4 | |a Confidence intervals | |
| 650 | 4 | |a Insulin | |
| 650 | 4 | |a Alzheimers disease | |
| 650 | 4 | |a Diabetes | |
| 650 | 4 | |a Cognitive ability | |
| 650 | 4 | |a Older people | |
| 650 | 4 | |a Health risk assessment | |
| 650 | 4 | |a Dementia | |
| 700 | 1 | |a McNicholas, Emily |4 oth | |
| 700 | 1 | |a Sinclair, Alan J |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of diabetes and its complications |d New York, NY : Elsevier, 1992 |g 30(2016), 8, Seite 1548-1554 |w (DE-627)170786293 |w (DE-600)1105840-7 |w (DE-576)038688239 |x 1056-8727 |7 nnns |
| 773 | 1 | 8 | |g volume:30 |g year:2016 |g number:8 |g pages:1548-1554 |
| 856 | 4 | 1 | |u http://dx.doi.org/10.1016/j.jdiacomp.2016.07.027 |3 Volltext |
| 856 | 4 | 2 | |u http://search.proquest.com/docview/1828222076 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a SSG-OLC-DE-84 | ||
| 912 | |a GBV_ILN_4219 | ||
| 951 | |a AR | ||
| 952 | |d 30 |j 2016 |e 8 |h 1548-1554 | ||