GW27-e1035 The effect of methylation of ATRAP gene on left ventricular hypertrophy in spontaneously hypertensive rats treated early with losartan

Objectives To investigate long-term influence of early treatment of spontaneously hypertensive rats (SHR) with losartan (Los) on blood pressure, left ventricular hypertrophy and expression of angiotensin type 1 receptor-associated protein (ATRAP) in myocardium, and to explore the role of DNA methylation in the long-term effect of Los..

Medienart:

Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:68

Enthalten in:

Journal of the American College of Cardiology - 68(2016), 16, Seite C37-C38

Sprache:

Englisch

Beteiligte Personen:

Tingjun, Wang [VerfasserIn]
Lian, Guili [Sonstige Person]
Xu, Changsheng [Sonstige Person]
Lin, Xu [Sonstige Person]
Chen, Wanru [Sonstige Person]
Xie, Liangdi [Sonstige Person]

Links:

Volltext
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Themen:

DNA methylation
Deoxyribonucleic acid--DNA
Genes
Hypertension
Protein synthesis
Proteins
Rodents

RVK:

RVK Klassifikation

doi:

10.1016/j.jacc.2016.07.139

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC1985320886