Access to the Pyrroloindoline Core via [3 + 2] Annulation as well as the Application in the Synthetic Approach to (±)-Minfiensine

A [3 + 2] formal cycloaddition reaction using aza-oxyallyl cation as a synthetic synthon was developed to construct the pyrroloindololine core. With this novel method, a variety of C3-substituted indoles were readily converted into the corresponding pyrroloindoline analogues at room temperature in the mixed solvents. To further demonstrate the utility of this method, a synthetic approach to the total synthesis of (±)-minfiensine was developed in quite concise fashion..

Medienart:

Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

Organic letters - 18(2016), 3, Seite 628

Sprache:

Englisch

Beteiligte Personen:

Liao, Xuebin [VerfasserIn]
Ji, Wenzhi [Sonstige Person]
Yao, Licheng [Sonstige Person]

Links:

www.ncbi.nlm.nih.gov

BKL:

35.50

RVK:

RVK Klassifikation

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

OLC1972239635