Spontaneous normalization of valve function after failed fibrinolytic therapy for left-sided prosthetic valve thrombosis
residual valve dysfunction after FT normalizes spontaneously in nearly one-half the patients, but the risk of major adverse events is prohibitively high, particularly among patients who do not show improvement in functional class after FT. [...]these patients should be triaged for early redo surgery irrespective of the reduction in transvalvular gradients. Pre- and post-treatment mitral EDG, mm Hg 14.3, 6.2[dagger] Pre- and post-treatment mitral MDG, mm Hg 25.5, 12[double dagger] Pre- and post-treatment aortic PSG, mm Hg 66.5, 39.5§ Pre- and post-treatment aortic MSG, mm Hg 38.2, 22.6|| Complete failure 18 (58.1) Partial response 13 (41.9) Table 1 Baseline Characteristics and Response to Fibrinolytic Therapy (N = 31) Values are mean ± SD, n (%), or median (IQR).EDG = end-diastolic gradient; INR = international normalized ratio; MDG = mean diastolic gradient; MSG = mean systolic gradient; NYHA = New York Heart Association; PSG = peak systolic gradient..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:65 |
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| Enthalten in: |
Journal of the American College of Cardiology - 65(2015), 14, Seite 1484-1485 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Airan, Balram [VerfasserIn] |
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| Links: |
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| RVK: |
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| doi: |
10.1016/j.jacc.2014.12.062 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC1969854642 |
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| 245 | 1 | 0 | |a Spontaneous normalization of valve function after failed fibrinolytic therapy for left-sided prosthetic valve thrombosis |
| 264 | 1 | |c 2015 | |
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| 520 | |a residual valve dysfunction after FT normalizes spontaneously in nearly one-half the patients, but the risk of major adverse events is prohibitively high, particularly among patients who do not show improvement in functional class after FT. [...]these patients should be triaged for early redo surgery irrespective of the reduction in transvalvular gradients. Pre- and post-treatment mitral EDG, mm Hg 14.3, 6.2[dagger] Pre- and post-treatment mitral MDG, mm Hg 25.5, 12[double dagger] Pre- and post-treatment aortic PSG, mm Hg 66.5, 39.5§ Pre- and post-treatment aortic MSG, mm Hg 38.2, 22.6|| Complete failure 18 (58.1) Partial response 13 (41.9) Table 1 Baseline Characteristics and Response to Fibrinolytic Therapy (N = 31) Values are mean ± SD, n (%), or median (IQR).EDG = end-diastolic gradient; INR = international normalized ratio; MDG = mean diastolic gradient; MSG = mean systolic gradient; NYHA = New York Heart Association; PSG = peak systolic gradient. | ||
| 650 | 4 | |a Heart Valve Prosthesis Implantation - adverse effects | |
| 650 | 4 | |a Thrombosis - diagnosis | |
| 650 | 4 | |a Thrombolytic Therapy - methods | |
| 650 | 4 | |a Thrombosis - therapy | |
| 650 | 4 | |a Thrombosis - physiopathology | |
| 650 | 4 | |a Surgery | |
| 650 | 4 | |a Heart attacks | |
| 650 | 4 | |a Drug therapy | |
| 650 | 4 | |a Studies | |
| 650 | 4 | |a Prostheses | |
| 650 | 4 | |a Developing countries--LDCs | |
| 650 | 4 | |a Thrombosis | |
| 650 | 4 | |a Confidence intervals | |
| 700 | 1 | |a Bahl, Vinay K |4 oth | |
| 700 | 1 | |a Karthikeyan, Ganesan |4 oth | |
| 700 | 1 | |a Devasenapathy, Niveditha |4 oth | |
| 700 | 1 | |a Senguttuvan, Nagendra Boopathy |4 oth | |
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| 773 | 1 | 8 | |g volume:65 |g year:2015 |g number:14 |g pages:1484-1485 |
| 856 | 4 | 1 | |u http://dx.doi.org/10.1016/j.jacc.2014.12.062 |3 Volltext |
| 856 | 4 | 2 | |u http://www.ncbi.nlm.nih.gov/pubmed/25857915 |
| 856 | 4 | 2 | |u http://search.proquest.com/docview/1674481415 |
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