Allergic disorders and socio‐economic status: a study of schoolchildren in an urban area of Makassar, Indonesia

In urban centres of developing countries, there is great variation in socio-economic status (SES) and lifestyle; however, little information is available on allergic disorders in groups with high- or low-SES within the same urban area. To determine the prevalence of allergic disorders and investigate risk factors related to them among high- and low-SES schoolchildren in Makassar, the capital city of South Sulawesi, Indonesia. This cross-sectional study was performed in 623 children originating from high- (N = 349) and low-SES (N = 274) schools. Information on reported allergic symptoms and potential factors associated with allergic disorders was obtained by questionnaire. Specific IgE and skin prick test (SPT) reactivity were determined against aeroallergens [Dermatophagoides pteronyssinus (HDM) and cockroach]. Total IgE and helminth infections were also assessed. The prevalence of SPT to any aeroallergens was significantly higher in high-SES than in low-SES school (25% vs. 8%, P < 0.001, respectively). However, specific IgE against cockroach and total IgE were significantly lower in high- than in low-SES children. Allergic symptoms were reported more often in low- compared to high-SES children. Specific IgE to aeroallergens significantly increased the risk of SPT positivity to the same aeroallergen in the high-, but not in the low-SES children. In the high- but not in low-SES, there was a significant positive association between SPT to HDM and wheeze. Similarly, cockroach skin reactivity and elevated BMI increased the risk of eczema in the high-SES children only. Skin prick test is higher in high-SES, whereas IgE and allergic symptoms are higher in low-SES children. Specific IgE is a risk factor for being SPT-positive, and SPT positivity is a risk factor for allergic symptoms but only in children of high- and not low-SES school. Therefore, the socio-economic status of a child might affect the diagnosis of allergic disease in a developing country..

Medienart:	Artikel

Erscheinungsjahr:	2015
Erschienen:	2015

Enthalten in:	Zur Gesamtaufnahme - volume:45
Enthalten in:	Clinical & experimental allergy - 45(2015), 7, Seite 1226-1236

Sprache:	Englisch

Beteiligte Personen:	Hamid, F [VerfasserIn] Wahyuni, S [Sonstige Person] Leeuwen, A [Sonstige Person] Ree, R [Sonstige Person] Yazdanbakhsh, M [Sonstige Person] Sartono, E [Sonstige Person]

Links:	Volltext onlinelibrary.wiley.com www.ncbi.nlm.nih.gov search.proquest.com

Themen:	Allergy Atopy Helminths Risk factors Socio‐economic status

doi:	10.1111/cea.12517

funding:
Förderinstitution / Projekttitel:

PPN (Katalog-ID):	OLC1965513832