Macular edema in Asian Indian premature infants with retinopathy of prematurity: Impact on visual acuity and refractive status after 1-year
To report the impact of transient, self-resolving, untreated "macular edema" detected on spectral domain optical coherence tomography in Asian Indian premature infants with retinopathy of prematurity (ROP) on visual acuity (VA) and refraction at 1-year of corrected age. Visual acuity and refraction of 11 infants with bilateral macular edema (Group A) was compared with gestational age-matched 16 infants with ROP without edema (Group B) and 17 preterms infants without ROP and without edema (Group C) at 3, 6, 9 and 12 months of corrected age using Teller Acuity Cards and cycloplegic retinoscopy. Sub-group analysis of the previously described pattern A and B macular edema was performed. Visual acuity was lower in infants with macular edema compared with the other two control groups throughout the study period, but statistically significant only at 3 months. Visual improvement in these infants was highest between the 3 rd and 6 th month and plateaued by the end of the 1 st year with acuity comparable to the other two groups. The edema cohort was more hyperopic compared to the other two groups between 3 and 12 months of age. Pattern A edema had worse VA compared to pattern B, although not statistically significant. Macular edema, although transient, caused reduced VA as early as 3 months of corrected age in Asian Indian premature infants weighing <2000 g at birth. The higher hyperopia in these infants is possibly due to visual disturbances caused at a critical time of fovealization. We hypothesize a recovery and feedback mechanism based on the principles of active emmetropization to explain our findings..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:63 |
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| Enthalten in: |
Indian journal of ophthalmology - 63(2015), 5, Seite 432-437 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Vinekar, Anand [VerfasserIn] |
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| Links: |
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| doi: |
10.4103/0301-4738.159879 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC1964664438 |
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| 245 | 1 | 0 | |a Macular edema in Asian Indian premature infants with retinopathy of prematurity: Impact on visual acuity and refractive status after 1-year |
| 264 | 1 | |c 2015 | |
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| 520 | |a To report the impact of transient, self-resolving, untreated "macular edema" detected on spectral domain optical coherence tomography in Asian Indian premature infants with retinopathy of prematurity (ROP) on visual acuity (VA) and refraction at 1-year of corrected age. Visual acuity and refraction of 11 infants with bilateral macular edema (Group A) was compared with gestational age-matched 16 infants with ROP without edema (Group B) and 17 preterms infants without ROP and without edema (Group C) at 3, 6, 9 and 12 months of corrected age using Teller Acuity Cards and cycloplegic retinoscopy. Sub-group analysis of the previously described pattern A and B macular edema was performed. Visual acuity was lower in infants with macular edema compared with the other two control groups throughout the study period, but statistically significant only at 3 months. Visual improvement in these infants was highest between the 3 rd and 6 th month and plateaued by the end of the 1 st year with acuity comparable to the other two groups. The edema cohort was more hyperopic compared to the other two groups between 3 and 12 months of age. Pattern A edema had worse VA compared to pattern B, although not statistically significant. Macular edema, although transient, caused reduced VA as early as 3 months of corrected age in Asian Indian premature infants weighing <2000 g at birth. The higher hyperopia in these infants is possibly due to visual disturbances caused at a critical time of fovealization. We hypothesize a recovery and feedback mechanism based on the principles of active emmetropization to explain our findings. | ||
| 650 | 4 | |a Influence | |
| 650 | 4 | |a Age | |
| 650 | 4 | |a Premature birth | |
| 650 | 4 | |a Metabolic disorders | |
| 650 | 4 | |a Morphology | |
| 650 | 4 | |a Statistical analysis | |
| 650 | 4 | |a Babies | |
| 650 | 4 | |a zeaxanthin | |
| 650 | 4 | |a Choroidal neovascularization | |
| 650 | 4 | |a spectral domain optical coherence tomography | |
| 650 | 4 | |a Age-related macular degeneration | |
| 650 | 4 | |a telemedicine | |
| 650 | 4 | |a vitreoretinal surgery | |
| 650 | 4 | |a Müller cells | |
| 650 | 4 | |a juxtafoveal retinal telangiectasia | |
| 650 | 4 | |a macular pigment | |
| 650 | 4 | |a idiopathic juxtafoveal telangiectasis | |
| 650 | 4 | |a visual acuity | |
| 650 | 4 | |a Emmetropization | |
| 650 | 4 | |a retina | |
| 650 | 4 | |a choroidal thickness | |
| 650 | 4 | |a ocular magnification | |
| 650 | 4 | |a RE1-994 | |
| 650 | 4 | |a lipofuscin | |
| 650 | 4 | |a external limiting membrane | |
| 650 | 4 | |a macular telangiectasia | |
| 650 | 4 | |a perifoveal telangiectasis | |
| 650 | 4 | |a retinopathy of prematurity | |
| 650 | 4 | |a en-face optical coherence tomography | |
| 650 | 4 | |a Adaptive optics | |
| 650 | 4 | |a lutein | |
| 650 | 4 | |a cone density | |
| 650 | 4 | |a Karnataka Internet-assisted Diagnosis of Retinopathy of Prematurity | |
| 650 | 4 | |a hand-held | |
| 650 | 4 | |a standard operating procedure | |
| 650 | 4 | |a swept source optical coherence tomography | |
| 650 | 4 | |a Central reading center | |
| 650 | 4 | |a Fundus autofluorescence | |
| 650 | 4 | |a foveal diameter | |
| 650 | 4 | |a Artifact | |
| 650 | 4 | |a myopia | |
| 650 | 4 | |a spectral-domain optical coherence tomography | |
| 650 | 4 | |a foveal slope | |
| 650 | 4 | |a Choroid | |
| 650 | 4 | |a Microscope-integrated optical coherence tomography | |
| 650 | 4 | |a randomized controlled trial | |
| 650 | 4 | |a Ophthalmology | |
| 650 | 4 | |a universal screening | |
| 650 | 4 | |a retinal imaging | |
| 650 | 4 | |a enhanced depth imaging technique | |
| 650 | 4 | |a Choroidal imaging | |
| 650 | 4 | |a subretinal neovascularization | |
| 650 | 4 | |a RESCAN | |
| 650 | 4 | |a macular edema | |
| 650 | 4 | |a digital imaging | |
| 650 | 4 | |a Cystoid macular edema | |
| 650 | 4 | |a parafoveal telangiectasis | |
| 650 | 4 | |a Community | |
| 650 | 4 | |a axial length | |
| 650 | 4 | |a retinal angiomatous proliferation | |
| 650 | 4 | |a retinal telangiectasis | |
| 650 | 4 | |a dexamethasone implant | |
| 650 | 4 | |a uveitis | |
| 650 | 4 | |a optical coherence tomography | |
| 650 | 4 | |a retinal dystrophies | |
| 650 | 4 | |a Ozurdex | |
| 650 | 4 | |a Medicine | |
| 650 | 4 | |a serous retinal detachment | |
| 650 | 4 | |a polypoidal choroidal vasculopathy | |
| 700 | 1 | |a Mangalesh, Shwetha |4 oth | |
| 700 | 1 | |a Jayadev, Chaitra |4 oth | |
| 700 | 1 | |a Bauer, Noel |4 oth | |
| 700 | 1 | |a Munusamy, Sivakumar |4 oth | |
| 700 | 1 | |a Kemmanu, Vasudha |4 oth | |
| 700 | 1 | |a Kurian, Mathew |4 oth | |
| 700 | 1 | |a Mahendradas, Padmamalini |4 oth | |
| 700 | 1 | |a Avadhani, Kavitha |4 oth | |
| 700 | 1 | |a Shetty, Bhujang |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t Indian journal of ophthalmology |d Mumbai : Medknow Publ., 1971 |g 63(2015), 5, Seite 432-437 |w (DE-627)166425842 |w (DE-600)187392-1 |x 0301-4738 |7 nnns |
| 773 | 1 | 8 | |g volume:63 |g year:2015 |g number:5 |g pages:432-437 |
| 856 | 4 | 1 | |u http://dx.doi.org/10.4103/0301-4738.159879 |3 Volltext |
| 856 | 4 | 2 | |u http://www.ncbi.nlm.nih.gov/pubmed/26139806 |
| 856 | 4 | 2 | |u http://search.proquest.com/docview/1696245959 |
| 856 | 4 | 2 | |u https://doaj.org/article/86085abd67474e858a8632ea5af58622 |
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