Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Early events during dengue virus (DENV) infection remain poorly understood. In this issue, Schaeffer and colleagues employ ex vivo human skin cells to investigate viral infection. They show that skin-resident immune cells are infected by DENV and that their infectability is increased in the inflammatory skin conditions (especially those in which IL-4 is released) that accompany the mosquito bites transmitting the virus..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:135 |
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| Enthalten in: |
The journal of investigative dermatology - 135(2015), 7, Seite 1711-1712 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ivory, Matthew O [VerfasserIn] |
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| Links: |
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| Themen: |
Antigen-Presenting Cells - immunology |
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| RVK: |
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| doi: |
10.1038/jid.2014.544 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
OLC1964639921 |
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| 100 | 1 | |a Ivory, Matthew O |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity |
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| 520 | |a Early events during dengue virus (DENV) infection remain poorly understood. In this issue, Schaeffer and colleagues employ ex vivo human skin cells to investigate viral infection. They show that skin-resident immune cells are infected by DENV and that their infectability is increased in the inflammatory skin conditions (especially those in which IL-4 is released) that accompany the mosquito bites transmitting the virus. | ||
| 650 | 4 | |a Skin Diseases, Viral - metabolism | |
| 650 | 4 | |a Antigen-Presenting Cells - immunology | |
| 650 | 4 | |a Dengue Virus - pathogenicity | |
| 650 | 4 | |a Epidermis - cytology | |
| 650 | 4 | |a Interleukin-4 - metabolism | |
| 700 | 1 | |a Birchall, James C |4 oth | |
| 700 | 1 | |a Piguet, Vincent |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t The journal of investigative dermatology |d New York, NY : Elsevier, 1938 |g 135(2015), 7, Seite 1711-1712 |w (DE-627)129269379 |w (DE-600)80136-7 |w (DE-576)014459825 |x 0022-202X |7 nnns |
| 773 | 1 | 8 | |g volume:135 |g year:2015 |g number:7 |g pages:1711-1712 |
| 856 | 4 | 1 | |u http://dx.doi.org/10.1038/jid.2014.544 |3 Volltext |
| 856 | 4 | 2 | |u http://www.ncbi.nlm.nih.gov/pubmed/26066889 |
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| 912 | |a GBV_ILN_2141 | ||
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