Livedoid Vasculopathy with Hyperhomocysteinemia Responding to Hyperbaric Oxygen Therapy
A 30-year-old male presented to the dermatology department with complaints of multiple ulcers over both legs of 6 years duration. The ulcers had a waxing and waning course with present exacerbation of lesions since 1 month. Dermatological examination revealed multiple ulcers distributed in a reticular pattern over medial and lateral aspects of both lower legs, extensor aspect of both ankles and dorsum of both feet. Multiple interspersed atrophic porcelain white scars were also present. Investigations revealed raised serum homocysteine levels. A skin biopsy from the ulcers showed features of livedoid vasculopathy. Following recurrence of lesions after oral corticosteroid therapy, the patient was given a course of hyperbaric oxygen therapy for the ulcers to which he responded very well. This case is being presented for the novel option of hyperbaric oxygen therapy in livedoid vasculopathy, which by itself is rarely reported in this part of the world..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:60 |
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| Enthalten in: |
Indian journal of dermatology - 60(2015), 5, Seite 524 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ray, Rahul [VerfasserIn] |
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| Links: |
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| doi: |
10.4103/0019-5154.159657 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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OLC196379334X |
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| 520 | |a A 30-year-old male presented to the dermatology department with complaints of multiple ulcers over both legs of 6 years duration. The ulcers had a waxing and waning course with present exacerbation of lesions since 1 month. Dermatological examination revealed multiple ulcers distributed in a reticular pattern over medial and lateral aspects of both lower legs, extensor aspect of both ankles and dorsum of both feet. Multiple interspersed atrophic porcelain white scars were also present. Investigations revealed raised serum homocysteine levels. A skin biopsy from the ulcers showed features of livedoid vasculopathy. Following recurrence of lesions after oral corticosteroid therapy, the patient was given a course of hyperbaric oxygen therapy for the ulcers to which he responded very well. This case is being presented for the novel option of hyperbaric oxygen therapy in livedoid vasculopathy, which by itself is rarely reported in this part of the world. | ||
| 540 | |a Nutzungsrecht: © COPYRIGHT 2015 Medknow Publications and Media Pvt. Ltd. | ||
| 650 | 4 | |a Leg | |
| 650 | 4 | |a Diagnosis | |
| 650 | 4 | |a Case studies | |
| 650 | 4 | |a Hyperhomocysteinemia | |
| 650 | 4 | |a Oxygen therapy | |
| 650 | 4 | |a Health aspects | |
| 650 | 4 | |a Ulcers | |
| 650 | 4 | |a Risk factors | |
| 650 | 4 | |a Care and treatment | |
| 650 | 4 | |a Patient outcomes | |
| 650 | 4 | |a Disease | |
| 650 | 4 | |a Ischemia | |
| 650 | 4 | |a Pathogenesis | |
| 650 | 4 | |a Hepatitis | |
| 650 | 4 | |a Oxygen | |
| 650 | 4 | |a Vitamin B | |
| 650 | 4 | |a Foot diseases | |
| 650 | 4 | |a Acids | |
| 650 | 4 | |a Mutation | |
| 650 | 4 | |a Homocysteine | |
| 650 | 4 | |a Immunoglobulins | |
| 700 | 1 | |a Sharma, Aseem |4 oth | |
| 700 | 1 | |a Vasudevan, Biju |4 oth | |
| 700 | 1 | |a Sridhar, Jandhyala |4 oth | |
| 700 | 1 | |a Deo, Rajeev |4 oth | |
| 700 | 1 | |a Mohanty, C S |4 oth | |
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| 856 | 4 | 2 | |u http://www.ncbi.nlm.nih.gov/pubmed/26538741 |
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