Tuberculosis during Pregnancy in Northern Israel, 2002-2012: Epidemiology and Clinical Practices
Atypical presentation of tuberculosis (TB) during pregnancy may cause diagnostic delay and adversely influence pregnancy outcome. To examine the incidence and clinical and epidemiological features of TB during pregnancy and investigate infection control measures at delivery and during the postpartum period. We retrospectively evaluated all reported cases of TB diagnosed during pregnancy to 6 months postpartum in Israel's Northern Health District (2002-2012). Active TB was detected in six patients; all were negative for human immunodeficiency virus (HIV). Two patients were diagnosed in the postpartum period, and four had pulmonary involvement. The average incidence during this period (3.9 per 100,000 pregnancies) was similar to that in the general population. Five patients were at high risk of contracting TB due to either recent immigration from a high-burden country or being in contact with another individual with active TB. Patients with pleuropulmonary involvement had prolonged cough and abnormal chest X-rays, without fever. Diagnosis was delayed for 3 to 7 months from symptom onset. Investigation of the newborn to rule out intrauterine infection was conducted in only one of four relevant cases. All patients were infected with organisms susceptible to all first-line drugs, and all were cured with standard therapy. There was a considerable delay in the diagnosis of TB among pregnant women, and investigation of the newborn upon delivery to rule out TB infection was routinely omitted. Effective management of TB during pregnancy and the postpartum period requires a multidisciplinary approach including an obstetrician, pediatrician, TB specialist, and public health physician..
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2015 |
|---|---|
| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:17 |
|---|---|
| Enthalten in: |
Israel Medical Association journal - 17(2015), 6, Seite 346 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Bishara, Hashem [VerfasserIn] |
|---|
| Links: |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
OLC1960857185 |
|---|
| LEADER | 01000caa a2200265 4500 | ||
|---|---|---|---|
| 001 | OLC1960857185 | ||
| 003 | DE-627 | ||
| 005 | 20230515120915.0 | ||
| 007 | tu | ||
| 008 | 160206s2015 xx ||||| 00| ||eng c | ||
| 028 | 5 | 2 | |a PQ20160617 |
| 035 | |a (DE-627)OLC1960857185 | ||
| 035 | |a (DE-599)GBVOLC1960857185 | ||
| 035 | |a (PRQ)p834-bec1bdaf09475d126a8b01b2322099c6b7ef9d1a4bc203487992e465840fd82c0 | ||
| 035 | |a (KEY)0393617120150000017000600346tuberculosisduringpregnancyinnorthernisrael2002201 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 610 |q ZDB |
| 084 | |a 44.00 |2 bkl | ||
| 100 | 1 | |a Bishara, Hashem |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Tuberculosis during Pregnancy in Northern Israel, 2002-2012: Epidemiology and Clinical Practices |
| 264 | 1 | |c 2015 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 520 | |a Atypical presentation of tuberculosis (TB) during pregnancy may cause diagnostic delay and adversely influence pregnancy outcome. To examine the incidence and clinical and epidemiological features of TB during pregnancy and investigate infection control measures at delivery and during the postpartum period. We retrospectively evaluated all reported cases of TB diagnosed during pregnancy to 6 months postpartum in Israel's Northern Health District (2002-2012). Active TB was detected in six patients; all were negative for human immunodeficiency virus (HIV). Two patients were diagnosed in the postpartum period, and four had pulmonary involvement. The average incidence during this period (3.9 per 100,000 pregnancies) was similar to that in the general population. Five patients were at high risk of contracting TB due to either recent immigration from a high-burden country or being in contact with another individual with active TB. Patients with pleuropulmonary involvement had prolonged cough and abnormal chest X-rays, without fever. Diagnosis was delayed for 3 to 7 months from symptom onset. Investigation of the newborn to rule out intrauterine infection was conducted in only one of four relevant cases. All patients were infected with organisms susceptible to all first-line drugs, and all were cured with standard therapy. There was a considerable delay in the diagnosis of TB among pregnant women, and investigation of the newborn upon delivery to rule out TB infection was routinely omitted. Effective management of TB during pregnancy and the postpartum period requires a multidisciplinary approach including an obstetrician, pediatrician, TB specialist, and public health physician. | ||
| 650 | 4 | |a Tuberculosis - diagnosis | |
| 650 | 4 | |a Pregnancy Complications, Infectious - epidemiology | |
| 650 | 4 | |a Tuberculosis - epidemiology | |
| 650 | 4 | |a Pregnancy Complications, Infectious - diagnosis | |
| 650 | 4 | |a Infectious Disease Transmission, Vertical - statistics & numerical data | |
| 650 | 4 | |a Antitubercular Agents - therapeutic use | |
| 650 | 4 | |a Pregnancy Complications, Infectious - drug therapy | |
| 650 | 4 | |a Tuberculosis - drug therapy | |
| 700 | 1 | |a Goldstein, Noam |4 oth | |
| 700 | 1 | |a Hakim, Marwan |4 oth | |
| 700 | 1 | |a Vinitsky, Olga |4 oth | |
| 700 | 1 | |a Shechter-Amram, Danit |4 oth | |
| 700 | 1 | |a Weiler-Ravell, Daniel |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |a ha- Histadderût hā-Refû'ît be-Yiśrā'ēl ; ID: gnd/1004821-2 |t Israel Medical Association journal |d Ramat Gan, 1999 |g 17(2015), 6, Seite 346 |w (DE-627)320469123 |w (DE-600)2008291-5 |x 1565-1088 |7 nnns |
| 773 | 1 | 8 | |g volume:17 |g year:2015 |g number:6 |g pages:346 |
| 856 | 4 | 2 | |u http://www.ncbi.nlm.nih.gov/pubmed/26233992 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a SSG-OLC-DE-84 | ||
| 912 | |a GBV_ILN_4219 | ||
| 936 | b | k | |a 44.00 |q AVZ |
| 951 | |a AR | ||
| 952 | |d 17 |j 2015 |e 6 |h 346 | ||