Hepatitis C core antigen testing: a reliable, quick, and potentially cost-effective alternative to hepatitis C polymerase chain reaction in diagnosing acute hepatitis C virus infection
Hepatitis C virus (HCV) is increasingly common among human immunodeficiency virus (HIV)-infected men who have sex with men. We evaluated the efficacy of HCV core antigen in diagnosing acute HCV in an HIV-infected cohort. Compared with HCV polymerase chain reaction, core antigen proved sensitive (100%) and specific (97.9%). As a quick, simple, and cost-effective test, it has considerable utility in screening for acute HCV..
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:60 |
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| Enthalten in: |
Clinical infectious diseases - 60(2015), 2, Seite 263 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cresswell, Fiona V [VerfasserIn] |
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| Links: |
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| doi: |
10.1093/cid/ciu782 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 245 | 1 | 0 | |a Hepatitis C core antigen testing: a reliable, quick, and potentially cost-effective alternative to hepatitis C polymerase chain reaction in diagnosing acute hepatitis C virus infection |
| 264 | 1 | |c 2015 | |
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| 520 | |a Hepatitis C virus (HCV) is increasingly common among human immunodeficiency virus (HIV)-infected men who have sex with men. We evaluated the efficacy of HCV core antigen in diagnosing acute HCV in an HIV-infected cohort. Compared with HCV polymerase chain reaction, core antigen proved sensitive (100%) and specific (97.9%). As a quick, simple, and cost-effective test, it has considerable utility in screening for acute HCV. | ||
| 540 | |a Nutzungsrecht: © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com. | ||
| 650 | 4 | |a Polymerase Chain Reaction - economics | |
| 650 | 4 | |a Polymerase Chain Reaction - methods | |
| 650 | 4 | |a Diagnostic Tests, Routine - economics | |
| 650 | 4 | |a RNA, Viral - blood | |
| 650 | 4 | |a Hepatitis C - diagnosis | |
| 650 | 4 | |a Diagnostic Tests, Routine - methods | |
| 650 | 4 | |a Immunoassay - methods | |
| 650 | 4 | |a Immunoassay - economics | |
| 650 | 4 | |a Viral Core Proteins - blood | |
| 650 | 4 | |a Diagnosis | |
| 650 | 4 | |a HIV patients | |
| 650 | 4 | |a Health aspects | |
| 650 | 4 | |a Risk factors | |
| 650 | 4 | |a Polymerase chain reaction | |
| 650 | 4 | |a Hepatitis C | |
| 650 | 4 | |a MSM (Men who have sex with men) | |
| 650 | 4 | |a Usage | |
| 650 | 4 | |a Hepatitis | |
| 650 | 4 | |a Homosexuality | |
| 650 | 4 | |a Antigens | |
| 650 | 4 | |a Men | |
| 650 | 4 | |a Reliability | |
| 700 | 1 | |a Fisher, Martin |4 oth | |
| 700 | 1 | |a Hughes, Daniel J |4 oth | |
| 700 | 1 | |a Shaw, Simon G |4 oth | |
| 700 | 1 | |a Homer, Gary |4 oth | |
| 700 | 1 | |a Hassan-Ibrahim, Mohammed O |4 oth | |
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| 856 | 4 | 2 | |u http://www.ncbi.nlm.nih.gov/pubmed/25301216 |
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