Comparative effectiveness of angioembolization versus open surgery in patients with blunt splenic injury
© 2024. The Author(s)..
The effectiveness and safety of transcatheter splenic artery embolization (SAE) compared to those of open surgery in patients with blunt splenic injury (BSI) remain unclear. This retrospective cohort-matched study utilized data from the Japan Trauma Data Bank recorded between 2004 and 2019. Patients with BSI who underwent SAE or open surgery were selected. A propensity score matching analysis was used to balance the baseline covariates and compare outcomes, including all-cause in-hospital mortality and spleen salvage. From 361,706 patients recorded in the data source, this study included 2,192 patients with BSI who underwent SAE or open surgery. A propensity score matching analysis was used to extract 377 matched pairs of patients. The in-hospital mortality rates (SAE, 11.6% vs. open surgery, 11.2%, adjusted relative risk (aRR): 0.64; 95% confidence interval [CI]: 0.38-1.09, p = 0.10) were similar in both the groups. However, spleen salvage was significantly less achieved in the open surgery group than in the SAE group (SAE, 87.1% vs. open surgery, 32.1%; aRR: 2.84, 95%CI: 2.29-3.51, p < 0.001). Survival rates did not significantly differ between BSI patients undergoing SAE and those undergoing open surgery. Nonetheless, SAE was notably associated with a higher likelihood of successful spleen salvage.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2024 |
---|---|
Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
---|---|
Enthalten in: |
Scientific reports - 14(2024), 1 vom: 16. Apr., Seite 8800 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Suzuki, Toshinao [VerfasserIn] |
---|
Links: |
---|
Themen: |
---|
Anmerkungen: |
Date Completed 18.04.2024 Date Revised 19.04.2024 published: Electronic Citation Status MEDLINE |
---|
doi: |
10.1038/s41598-024-59420-w |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM371166896 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | NLM371166896 | ||
003 | DE-627 | ||
005 | 20240419232812.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240417s2024 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1038/s41598-024-59420-w |2 doi | |
028 | 5 | 2 | |a pubmed24n1380.xml |
035 | |a (DE-627)NLM371166896 | ||
035 | |a (NLM)38627581 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Suzuki, Toshinao |e verfasserin |4 aut | |
245 | 1 | 0 | |a Comparative effectiveness of angioembolization versus open surgery in patients with blunt splenic injury |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 18.04.2024 | ||
500 | |a Date Revised 19.04.2024 | ||
500 | |a published: Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a © 2024. The Author(s). | ||
520 | |a The effectiveness and safety of transcatheter splenic artery embolization (SAE) compared to those of open surgery in patients with blunt splenic injury (BSI) remain unclear. This retrospective cohort-matched study utilized data from the Japan Trauma Data Bank recorded between 2004 and 2019. Patients with BSI who underwent SAE or open surgery were selected. A propensity score matching analysis was used to balance the baseline covariates and compare outcomes, including all-cause in-hospital mortality and spleen salvage. From 361,706 patients recorded in the data source, this study included 2,192 patients with BSI who underwent SAE or open surgery. A propensity score matching analysis was used to extract 377 matched pairs of patients. The in-hospital mortality rates (SAE, 11.6% vs. open surgery, 11.2%, adjusted relative risk (aRR): 0.64; 95% confidence interval [CI]: 0.38-1.09, p = 0.10) were similar in both the groups. However, spleen salvage was significantly less achieved in the open surgery group than in the SAE group (SAE, 87.1% vs. open surgery, 32.1%; aRR: 2.84, 95%CI: 2.29-3.51, p < 0.001). Survival rates did not significantly differ between BSI patients undergoing SAE and those undergoing open surgery. Nonetheless, SAE was notably associated with a higher likelihood of successful spleen salvage | ||
650 | 4 | |a Journal Article | |
700 | 1 | |a Shiraishi, Atsushi |e verfasserin |4 aut | |
700 | 1 | |a Ito, Kensuke |e verfasserin |4 aut | |
700 | 1 | |a Otomo, Yasuhiro |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Scientific reports |d 2011 |g 14(2024), 1 vom: 16. Apr., Seite 8800 |w (DE-627)NLM215703936 |x 2045-2322 |7 nnns |
773 | 1 | 8 | |g volume:14 |g year:2024 |g number:1 |g day:16 |g month:04 |g pages:8800 |
856 | 4 | 0 | |u http://dx.doi.org/10.1038/s41598-024-59420-w |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 14 |j 2024 |e 1 |b 16 |c 04 |h 8800 |