Isotretinoin-unresponsive acne as a sign of a congenital disorder : a case of 21-hydroxylase deficiency
Copyright © 2024, the Author(s)..
Acne is a multifactorial and common disorder among young people and a frequent reason for dermatology consultation. When moderate-to-severe acne is not responsive to conventional treatments, oral isotretinoin is a very effective solution. However, there are cases in which this treatment fails to produce the expected results. In this case, an 18-year-old male patient with acne, unresponsive to traditional acne therapies, experienced only a partial benefit from oral isotretinoin. Endocrinology consultation and hormonal work-up revealed androgen metabolism anomalies suggestive of a non-classical form of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. In this case report, the authors discuss when to suspect, how to diagnose, and how to manage similar cases.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2024 |
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Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
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Enthalten in: |
Dermatology reports - 16(2024), 1 vom: 12. März, Seite 9717 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Marzola, Elisa [VerfasserIn] |
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Links: |
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Themen: |
21-hydroxylase deficiency |
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Anmerkungen: |
Date Revised 25.04.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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doi: |
10.4081/dr.2023.9717 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM371124964 |
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