Ketogenic diet therapies as a non-pharmacological adjuvant in resistant epilepsy : retrospective analysis of adult outpatients in Colombia
Twelve patients between 18 and 53 years of age were included. MAD plus nutritional supplementation was administered to 75% (n = 10) of the participants, one (8.3%) received MAD alone, and 16.7 (n = 2) received Classic Ketogenic Diet (cKD) plus nutritional supplementation. Oral nutritional supplementation, administered in the outpatient setting, provided patients with between 31 and 55% of the total caloric value. In the first month of KDT treatment, 83.3% (n = 10) of patients reduced the number of weekly seizures by 40% (median). At six months of treatment, 75% of patients had at least halved the number of weekly seizures. At 12 months of treatment, the number of weekly seizures had been reduced by 85.7% (median). KDT was well tolerated, and there was no need to discontinue treatment. This study provides real-world information on the use of KDT, particularly MAD in adults, in developing countries. Future studies in larger cohorts will provide further information on different types of KDT, adherence, and patient-reported outcomes.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Nutritional neuroscience - (2024) vom: 15. Apr., Seite 1-7 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ballesteros Tapias, Jennifer Katherine [VerfasserIn] |
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| Links: |
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| Themen: |
Adult |
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| Anmerkungen: |
Date Revised 16.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1080/1028415X.2024.2336716 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM371120454 |
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| 100 | 1 | |a Ballesteros Tapias, Jennifer Katherine |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Ketogenic diet therapies as a non-pharmacological adjuvant in resistant epilepsy |b retrospective analysis of adult outpatients in Colombia |
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| 520 | |a Twelve patients between 18 and 53 years of age were included. MAD plus nutritional supplementation was administered to 75% (n = 10) of the participants, one (8.3%) received MAD alone, and 16.7 (n = 2) received Classic Ketogenic Diet (cKD) plus nutritional supplementation. Oral nutritional supplementation, administered in the outpatient setting, provided patients with between 31 and 55% of the total caloric value. In the first month of KDT treatment, 83.3% (n = 10) of patients reduced the number of weekly seizures by 40% (median). At six months of treatment, 75% of patients had at least halved the number of weekly seizures. At 12 months of treatment, the number of weekly seizures had been reduced by 85.7% (median). KDT was well tolerated, and there was no need to discontinue treatment. This study provides real-world information on the use of KDT, particularly MAD in adults, in developing countries. Future studies in larger cohorts will provide further information on different types of KDT, adherence, and patient-reported outcomes | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Drug resistant epilepsy | |
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| 650 | 4 | |a diet | |
| 650 | 4 | |a epilepsy and observational study | |
| 650 | 4 | |a ketogenic diet therapies | |
| 650 | 4 | |a modified atkins diet | |
| 700 | 1 | |a Conde Hurtado, Diana Isabel |e verfasserin |4 aut | |
| 700 | 1 | |a Castaño, Luz Helena |e verfasserin |4 aut | |
| 700 | 1 | |a Pérez, Adriana Martínez |e verfasserin |4 aut | |
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