Temporal stability of tongue microbiota in older patients - A pilot study
© 2024 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V..
Background/purpose: Healthy states of human microbiota depend on a stable community of symbiotic microbes irrespective of external challenges from the environment. Thus, long-term stability of the oral microbiota is of importance, particularly for older patient populations.
Materials and methods: We used next-generation sequencing (NGS) to examine the tongue microbiota of 18 individuals receiving long-term care over a 10-month period.
Results: Beta diversity analysis demonstrated temporal stability of the tongue microbiota, as microbial compositions from all time points were indistinguishable from each other (P = 0.0887). However, significant individual variation in microbial composition (P = 0.0001) was observed, underscoring the presence of a unique microbial profile for each patient.
Conclusion: The temporal dynamics of tongue microbiota exhibit long-term stability, providing diagnostic implications for oral diseases within older patient populations.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
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| Enthalten in: |
Journal of dental sciences - 19(2024), 2 vom: 10. Apr., Seite 1087-1095 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Tsai, Fa-Tzu [VerfasserIn] |
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| Links: |
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| Themen: |
16S rRNA |
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| Anmerkungen: |
Date Revised 25.04.2024 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.jds.2024.01.012 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM371074665 |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2024 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V. | ||
| 520 | |a Background/purpose: Healthy states of human microbiota depend on a stable community of symbiotic microbes irrespective of external challenges from the environment. Thus, long-term stability of the oral microbiota is of importance, particularly for older patient populations | ||
| 520 | |a Materials and methods: We used next-generation sequencing (NGS) to examine the tongue microbiota of 18 individuals receiving long-term care over a 10-month period | ||
| 520 | |a Results: Beta diversity analysis demonstrated temporal stability of the tongue microbiota, as microbial compositions from all time points were indistinguishable from each other (P = 0.0887). However, significant individual variation in microbial composition (P = 0.0001) was observed, underscoring the presence of a unique microbial profile for each patient | ||
| 520 | |a Conclusion: The temporal dynamics of tongue microbiota exhibit long-term stability, providing diagnostic implications for oral diseases within older patient populations | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a 16S rRNA | |
| 650 | 4 | |a Amplicon sequence variant | |
| 650 | 4 | |a Older patient | |
| 650 | 4 | |a Oral microbiota | |
| 650 | 4 | |a Temporal stability | |
| 700 | 1 | |a Yang, Cheng-Chieh |e verfasserin |4 aut | |
| 700 | 1 | |a Lin, Yu-Cheng |e verfasserin |4 aut | |
| 700 | 1 | |a Hsu, Ming-Lun |e verfasserin |4 aut | |
| 700 | 1 | |a Hong, Guang |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Mu-Chen |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Ding-Han |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Lin-Jack |e verfasserin |4 aut | |
| 700 | 1 | |a Lin, Chiu-Tzu |e verfasserin |4 aut | |
| 700 | 1 | |a Hsu, Wun-Eng |e verfasserin |4 aut | |
| 700 | 1 | |a Tu, Hsi-Feng |e verfasserin |4 aut | |
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