Concurrent myocardial infarction in the setting of thrombotic thrombocytopenic purpura secondary to systemic lupus erythematosus : A case report

© 2024 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd..

Key Clinical Message: In acute thrombotic thrombocytopenic purpura (TTP), apart from urgent treatment, assessing the patient's medical history, especially conditions like systemic lupus erythematosus that could trigger TTP, is crucial. Rarely, TTP patients may experience cardiac conditions as severe as a myocardial infarction.

Abstract: A 45-year-old woman manifested severe and acute thrombotic thrombocytopenic purpura (TTP) of unknown origin. The patient's symptoms, the laboratory data, the detection of the reduction in ADAMTS13 activity, and the presence of schistocytes on the peripheral smear confirmed the diagnosis. The patient was then planned for therapeutic plasma exchange (TPE). Prior to the scheduled TPE, she suddenly experienced extreme shortness of breath and chest pain. An electrocardiogram was obtained immediately after reporting signs of an inferior myocardial infarction. Further examinations to acquire information about the patient's underlying medical conditions in order to study the secondary causes of TTP, combined with the results of the laboratory tests, resulted in the patient being diagnosed with systemic lupus erythematosus.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:12

Enthalten in:

Clinical case reports - 12(2024), 4 vom: 15. Apr., Seite e8751

Sprache:

Englisch

Beteiligte Personen:

Azadbakht, Saleh [VerfasserIn]
Amidi, Bardia [VerfasserIn]
Naderi, Narges [VerfasserIn]
Sharifaskari, Anwar [VerfasserIn]
Hatami, Mahtab [VerfasserIn]

Links:

Volltext

Themen:

Case Reports
Case report
Myocardial infarction
Systemic lupus erythematosus
Thrombotic thrombocytopenic purpura

Anmerkungen:

Date Revised 25.04.2024

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.1002/ccr3.8751

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM371063981