Incidences of newly diagnosed childhood diabetes and onset severity : a multicenter regional study in Thailand over two decades and during the COVID-19 pandemic
© 2024 Walter de Gruyter GmbH, Berlin/Boston..
OBJECTIVES: While global incidence rates (IR) of childhood diabetes are increasing, there is a notable lack of current information on the incidence of childhood-onset diabetes in Thailand. This study aims to illustrate the age-standardized IR and types of childhood diabetes using multicenter regional data in Northern Thailand from 2005 to 2022 and to assess the impact of the COVID-19 pandemic.
METHODS: Data on newly diagnosed childhood diabetes were retrospectively collected between 2005 and 2016 and prospectively recorded for all incident cases between 2016 and 2022. The capture-recapture method was applied to estimate the completeness of ascertainment. The age-standardized IR of diabetes was calculated. The IR of diabetes and the prevalence/severity of DKA at onset were compared between the pre-pandemic and pandemic periods.
RESULTS: Among 210 patients, type 1 diabetes (T1D) accounted for 56.2 %, type 2 diabetes (T2D) for 39 %, and other types for 4.8 %. The T1D age-standardized IR significantly increased from 0.30 in 2005 to 3.11/100,000 person/year in 2022, mirroring the T2D trend, which increased from 0.33 to 3.15/100,000 person/year. The average T1D age-standardized IR, including the prevalence/severity of DKA at diagnosis, did not significantly differ between the pre-pandemic and pandemic periods (2.11 vs. 2.36/100,000 person/year, p-value=0.67). However, the average T2D age-standardized IR significantly increased from 0.83 to 2.15/100,000 person/year during the pandemic (p-value=0.0057).
CONCLUSIONS: This study highlights an increased incidence of childhood T1D and T2D in Northern Thailand over a two-decade period. Notably, during the COVID-19 pandemic, the T1D incidence remained stable, while a significant rise in T2D incidence was observed.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2024 |
---|---|
Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
---|---|
Enthalten in: |
Journal of pediatric endocrinology & metabolism : JPEM - (2024) vom: 16. Apr. |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Sinthuprasith, Pattharaporn [VerfasserIn] |
---|
Links: |
---|
Themen: |
COVID-19 |
---|
Anmerkungen: |
Date Revised 14.04.2024 published: Print-Electronic Citation Status Publisher |
---|
doi: |
10.1515/jpem-2024-0042 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM371046572 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM371046572 | ||
003 | DE-627 | ||
005 | 20240415234354.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240415s2024 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1515/jpem-2024-0042 |2 doi | |
028 | 5 | 2 | |a pubmed24n1376.xml |
035 | |a (DE-627)NLM371046572 | ||
035 | |a (NLM)38615333 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Sinthuprasith, Pattharaporn |e verfasserin |4 aut | |
245 | 1 | 0 | |a Incidences of newly diagnosed childhood diabetes and onset severity |b a multicenter regional study in Thailand over two decades and during the COVID-19 pandemic |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Revised 14.04.2024 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status Publisher | ||
520 | |a © 2024 Walter de Gruyter GmbH, Berlin/Boston. | ||
520 | |a OBJECTIVES: While global incidence rates (IR) of childhood diabetes are increasing, there is a notable lack of current information on the incidence of childhood-onset diabetes in Thailand. This study aims to illustrate the age-standardized IR and types of childhood diabetes using multicenter regional data in Northern Thailand from 2005 to 2022 and to assess the impact of the COVID-19 pandemic | ||
520 | |a METHODS: Data on newly diagnosed childhood diabetes were retrospectively collected between 2005 and 2016 and prospectively recorded for all incident cases between 2016 and 2022. The capture-recapture method was applied to estimate the completeness of ascertainment. The age-standardized IR of diabetes was calculated. The IR of diabetes and the prevalence/severity of DKA at onset were compared between the pre-pandemic and pandemic periods | ||
520 | |a RESULTS: Among 210 patients, type 1 diabetes (T1D) accounted for 56.2 %, type 2 diabetes (T2D) for 39 %, and other types for 4.8 %. The T1D age-standardized IR significantly increased from 0.30 in 2005 to 3.11/100,000 person/year in 2022, mirroring the T2D trend, which increased from 0.33 to 3.15/100,000 person/year. The average T1D age-standardized IR, including the prevalence/severity of DKA at diagnosis, did not significantly differ between the pre-pandemic and pandemic periods (2.11 vs. 2.36/100,000 person/year, p-value=0.67). However, the average T2D age-standardized IR significantly increased from 0.83 to 2.15/100,000 person/year during the pandemic (p-value=0.0057) | ||
520 | |a CONCLUSIONS: This study highlights an increased incidence of childhood T1D and T2D in Northern Thailand over a two-decade period. Notably, during the COVID-19 pandemic, the T1D incidence remained stable, while a significant rise in T2D incidence was observed | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a COVID-19 | |
650 | 4 | |a childhood diabetes | |
650 | 4 | |a incidence of diabetes | |
700 | 1 | |a Wejaphikul, Karn |e verfasserin |4 aut | |
700 | 1 | |a Puttawong, Dolrutai |e verfasserin |4 aut | |
700 | 1 | |a Tang-Ngam, Hataitip |e verfasserin |4 aut | |
700 | 1 | |a Sanrattana, Naphatsorn |e verfasserin |4 aut | |
700 | 1 | |a Unachak, Kevalee |e verfasserin |4 aut | |
700 | 1 | |a Dejkhamron, Prapai |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of pediatric endocrinology & metabolism : JPEM |d 1995 |g (2024) vom: 16. Apr. |w (DE-627)NLM07560924X |x 2191-0251 |7 nnns |
773 | 1 | 8 | |g year:2024 |g day:16 |g month:04 |
856 | 4 | 0 | |u http://dx.doi.org/10.1515/jpem-2024-0042 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |j 2024 |b 16 |c 04 |