Neuropathic pain, mood, and stress-related disorders : A literature review of comorbidity and co-pathogenesis
Copyright © 2024 Elsevier Ltd. All rights reserved..
Neuropathic pain can be caused by multiple factors, and its prevalence can reach 10% of the global population. It is becoming increasingly evident that limited or short-lasting response to treatments for neuropathic pain is associated with psychological factors, which include psychiatric comorbidities known to affect quality of life. It is estimated that 60% of patients with neuropathic pain also experience depression, anxiety, and stress symptoms. Altered mood, including stress, can be a consequence of several painful conditions but can also favor pain chronicization when preexisting. Despite the apparent tight connection between clinical pain and mood/stress disorders, the exact physiological mechanisms remain unclear. This review aims to provide an overview of state-of-the-art research on the mechanisms of pain related to the pathophysiology of depression, anxiety, and stress disorders.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:161 |
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| Enthalten in: |
Neuroscience and biobehavioral reviews - 161(2024) vom: 16. Apr., Seite 105673 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Vieira, Willians Fernando [VerfasserIn] |
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| Links: |
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| Themen: |
Anxiety |
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| Anmerkungen: |
Date Revised 21.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.neubiorev.2024.105673 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Neuropathic pain can be caused by multiple factors, and its prevalence can reach 10% of the global population. It is becoming increasingly evident that limited or short-lasting response to treatments for neuropathic pain is associated with psychological factors, which include psychiatric comorbidities known to affect quality of life. It is estimated that 60% of patients with neuropathic pain also experience depression, anxiety, and stress symptoms. Altered mood, including stress, can be a consequence of several painful conditions but can also favor pain chronicization when preexisting. Despite the apparent tight connection between clinical pain and mood/stress disorders, the exact physiological mechanisms remain unclear. This review aims to provide an overview of state-of-the-art research on the mechanisms of pain related to the pathophysiology of depression, anxiety, and stress disorders | ||
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| 650 | 4 | |a Depression | |
| 650 | 4 | |a Mood disorders | |
| 650 | 4 | |a Neuropathic pain | |
| 650 | 4 | |a Stress | |
| 700 | 1 | |a Coelho, David Richer Araujo |e verfasserin |4 aut | |
| 700 | 1 | |a Litwiler, Scott Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a McEachern, Kayla Marie |e verfasserin |4 aut | |
| 700 | 1 | |a Clancy, Julie A |e verfasserin |4 aut | |
| 700 | 1 | |a Morales-Quezada, Leon |e verfasserin |4 aut | |
| 700 | 1 | |a Cassano, Paolo |e verfasserin |4 aut | |
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