A silicone disc for liver retraction in laparoscopic gastrectomy reduces the postoperative increase in the liver enzyme level
© 2024. The Author(s) under exclusive licence to Springer Nature Singapore Pte Ltd..
PURPOSE: To compare changes in liver enzyme levels on postoperative day 1 between patients with and without silicone disc (SD) use during liver retraction in laparoscopic gastrectomy for gastric cancer and laparoscopic gastric mobilization for esophageal cancer.
METHODS: This prospective randomized controlled phase II trial was conducted between June 30, 2020, and November 30, 2022, to investigate the benefits of using an SD with a Nathanson liver retractor (NLR) compared with those using an NLR in laparoscopic gastrectomy and gastric mobilization. The primary endpoint was the change in transaminase level on postoperative day 1.
RESULTS: A total of 86 patients received randomized assignments and were included in the analysis, with 44 assigned to the SD (-) group and 42 to the SD (+) group. On postoperative day 1, the SD (+) group showed a significantly lower increase in the aspartate aminotransferase levels than the SD (-) group (SD [+], 94.4% vs. SD [-], 179.8%; p = 0.012). Similarly, the SD (+) group showed a significantly lower increase in alanine aminotransferase levels than the SD (-) group (SD [+], 71.6% vs. SD [-], 201.5%; p = 0.014).
CONCLUSION: In laparoscopic gastrectomy, the use of an SD combined with an NLR appears to mitigate postoperative liver dysfunction.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Surgery today - (2024) vom: 12. Apr. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Soneda, Wataru [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Revised 12.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1007/s00595-024-02834-w |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM370967100 |
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| 245 | 1 | 2 | |a A silicone disc for liver retraction in laparoscopic gastrectomy reduces the postoperative increase in the liver enzyme level |
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| 520 | |a © 2024. The Author(s) under exclusive licence to Springer Nature Singapore Pte Ltd. | ||
| 520 | |a PURPOSE: To compare changes in liver enzyme levels on postoperative day 1 between patients with and without silicone disc (SD) use during liver retraction in laparoscopic gastrectomy for gastric cancer and laparoscopic gastric mobilization for esophageal cancer | ||
| 520 | |a METHODS: This prospective randomized controlled phase II trial was conducted between June 30, 2020, and November 30, 2022, to investigate the benefits of using an SD with a Nathanson liver retractor (NLR) compared with those using an NLR in laparoscopic gastrectomy and gastric mobilization. The primary endpoint was the change in transaminase level on postoperative day 1 | ||
| 520 | |a RESULTS: A total of 86 patients received randomized assignments and were included in the analysis, with 44 assigned to the SD (-) group and 42 to the SD (+) group. On postoperative day 1, the SD (+) group showed a significantly lower increase in the aspartate aminotransferase levels than the SD (-) group (SD [+], 94.4% vs. SD [-], 179.8%; p = 0.012). Similarly, the SD (+) group showed a significantly lower increase in alanine aminotransferase levels than the SD (-) group (SD [+], 71.6% vs. SD [-], 201.5%; p = 0.014) | ||
| 520 | |a CONCLUSION: In laparoscopic gastrectomy, the use of an SD combined with an NLR appears to mitigate postoperative liver dysfunction | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Gastrectomy | |
| 650 | 4 | |a Gastric mobilization | |
| 650 | 4 | |a Silicone disc | |
| 700 | 1 | |a Booka, Eisuke |e verfasserin |4 aut | |
| 700 | 1 | |a Haneda, Ryoma |e verfasserin |4 aut | |
| 700 | 1 | |a Kawata, Sanshiro |e verfasserin |4 aut | |
| 700 | 1 | |a Murakami, Tomohiro |e verfasserin |4 aut | |
| 700 | 1 | |a Matsumoto, Tomohiro |e verfasserin |4 aut | |
| 700 | 1 | |a Morita, Yoshifumi |e verfasserin |4 aut | |
| 700 | 1 | |a Kikuchi, Hirotoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Hiramatsu, Yoshihiro |e verfasserin |4 aut | |
| 700 | 1 | |a Takeuchi, Hiroya |e verfasserin |4 aut | |
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