Preoperative anaemia in distal pancreatectomy : a propensity-score matched analysis
© 2024. The Author(s)..
BACKGROUND: Preoperative anaemia is a prevalent morbidity predictor that adversely affects short- and long-term outcomes of patients undergoing surgery. This analysis aimed to investigate preoperative anaemia and its detrimental effects on patients after distal pancreatectomy.
MATERIAL AND METHODS: The present study was a propensity-score match analysis of 286 consecutive patients undergoing distal pancreatectomy. Patients were screened for preoperative anaemia and classified according to WHO recommendations. The primary outcome measure was overall morbidity. The secondary endpoints were in-hospital mortality and rehospitalization.
RESULTS: The preoperative anaemia rate before matching was 34.3% (98 patients), and after matching a total of 127 patients (non-anaemic 42 vs. anaemic 85) were included. Anaemic patients had significantly more postoperative major complications (54.1% vs. 23.8%; p < 0.01), a higher comprehensive complication index (26.2 vs. 4.3; p < 0.01), and higher in-hospital mortality rate (14.1% vs. 2.4%; p = 0.04). Multivariate regression analysis confirmed these findings and identified preoperative anaemia as a strong independent risk factor for postoperative major morbidity (OR 4.047; 95% CI: 1.587-10.320; p < 0.01).
CONCLUSION: The current propensity-score matched analysis strongly considered preoperative anaemia as a risk factor for major complications following distal pancreatectomy. Therefore, an intense preoperative anaemia workup should be increasingly prioritised.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:409 |
|---|---|
| Enthalten in: |
Langenbeck's archives of surgery - 409(2024), 1 vom: 11. Apr., Seite 119 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Radulova-Mauersberger, Olga [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Anaemia |
|---|
| Anmerkungen: |
Date Completed 12.04.2024 Date Revised 25.04.2024 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s00423-024-03300-4 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM370918738 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM370918738 | ||
| 003 | DE-627 | ||
| 005 | 20240425233910.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240411s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00423-024-03300-4 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1386.xml |
| 035 | |a (DE-627)NLM370918738 | ||
| 035 | |a (NLM)38602554 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Radulova-Mauersberger, Olga |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Preoperative anaemia in distal pancreatectomy |b a propensity-score matched analysis |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 12.04.2024 | ||
| 500 | |a Date Revised 25.04.2024 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2024. The Author(s). | ||
| 520 | |a BACKGROUND: Preoperative anaemia is a prevalent morbidity predictor that adversely affects short- and long-term outcomes of patients undergoing surgery. This analysis aimed to investigate preoperative anaemia and its detrimental effects on patients after distal pancreatectomy | ||
| 520 | |a MATERIAL AND METHODS: The present study was a propensity-score match analysis of 286 consecutive patients undergoing distal pancreatectomy. Patients were screened for preoperative anaemia and classified according to WHO recommendations. The primary outcome measure was overall morbidity. The secondary endpoints were in-hospital mortality and rehospitalization | ||
| 520 | |a RESULTS: The preoperative anaemia rate before matching was 34.3% (98 patients), and after matching a total of 127 patients (non-anaemic 42 vs. anaemic 85) were included. Anaemic patients had significantly more postoperative major complications (54.1% vs. 23.8%; p < 0.01), a higher comprehensive complication index (26.2 vs. 4.3; p < 0.01), and higher in-hospital mortality rate (14.1% vs. 2.4%; p = 0.04). Multivariate regression analysis confirmed these findings and identified preoperative anaemia as a strong independent risk factor for postoperative major morbidity (OR 4.047; 95% CI: 1.587-10.320; p < 0.01) | ||
| 520 | |a CONCLUSION: The current propensity-score matched analysis strongly considered preoperative anaemia as a risk factor for major complications following distal pancreatectomy. Therefore, an intense preoperative anaemia workup should be increasingly prioritised | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Anaemia | |
| 650 | 4 | |a Blood transfusion | |
| 650 | 4 | |a CCI | |
| 650 | 4 | |a Distal pancreatic resection | |
| 650 | 4 | |a Pancreatic disease | |
| 700 | 1 | |a von Bechtolsheim, Felix |e verfasserin |4 aut | |
| 700 | 1 | |a Teske, Christian |e verfasserin |4 aut | |
| 700 | 1 | |a Hempel, Sebastian |e verfasserin |4 aut | |
| 700 | 1 | |a Kroesen, Louisa |e verfasserin |4 aut | |
| 700 | 1 | |a Pecqueux, Mathieu |e verfasserin |4 aut | |
| 700 | 1 | |a Kahlert, Christoph |e verfasserin |4 aut | |
| 700 | 1 | |a Weitz, Jürgen |e verfasserin |4 aut | |
| 700 | 1 | |a Distler, Marius |e verfasserin |4 aut | |
| 700 | 1 | |a Oehme, Florian |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Langenbeck's archives of surgery |d 1998 |g 409(2024), 1 vom: 11. Apr., Seite 119 |w (DE-627)NLM095673148 |x 1435-2451 |7 nnns |
| 773 | 1 | 8 | |g volume:409 |g year:2024 |g number:1 |g day:11 |g month:04 |g pages:119 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00423-024-03300-4 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 409 |j 2024 |e 1 |b 11 |c 04 |h 119 | ||