The catalytic triad of rice NARROW LEAF1 involves H234
© 2024. The Author(s), under exclusive licence to Springer Nature Limited..
NARROW LEAF1 (NAL1) exerts a multifaceted influence on leaf morphology and crop yield. Recent crystal study proposed that histidine 233 (H233) is part of the catalytic triad. Here we report that unlike suggested previously, H234 instead of H233 is a component of the catalytic triad alongside residues D291 and S385 in NAL1. Remarkably, residue 233 unexpectedly plays a pivotal role in regulating NAL1's proteolytic activity. These findings establish a strong foundation for utilizing NAL1 in breeding programs aimed at improving crop yield.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Nature plants - (2024) vom: 10. Apr. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Huang, Ling-Yun [VerfasserIn] |
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Date Revised 10.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1038/s41477-024-01668-1 |
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| PPN (Katalog-ID): |
NLM370895843 |
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| 520 | |a © 2024. The Author(s), under exclusive licence to Springer Nature Limited. | ||
| 520 | |a NARROW LEAF1 (NAL1) exerts a multifaceted influence on leaf morphology and crop yield. Recent crystal study proposed that histidine 233 (H233) is part of the catalytic triad. Here we report that unlike suggested previously, H234 instead of H233 is a component of the catalytic triad alongside residues D291 and S385 in NAL1. Remarkably, residue 233 unexpectedly plays a pivotal role in regulating NAL1's proteolytic activity. These findings establish a strong foundation for utilizing NAL1 in breeding programs aimed at improving crop yield | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Chen, Wei-Fei |e verfasserin |4 aut | |
| 700 | 1 | |a Ai, Xia |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Hai-Hong |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Ze-Lin |e verfasserin |4 aut | |
| 700 | 1 | |a Hou, Xi-Miao |e verfasserin |4 aut | |
| 700 | 1 | |a Fossé, Philippe |e verfasserin |4 aut | |
| 700 | 1 | |a Mauffret, Olivier |e verfasserin |4 aut | |
| 700 | 1 | |a Lei, Dong-Sheng |e verfasserin |4 aut | |
| 700 | 1 | |a Rety, Stephane |e verfasserin |4 aut | |
| 700 | 1 | |a Xi, Xu-Guang |e verfasserin |4 aut | |
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