Artificial intelligence in kidney transplant pathology

© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature..

BACKGROUND: Artificial intelligence (AI) systems have showed promising results in digital pathology, including digital nephropathology and specifically also kidney transplant pathology.

AIM: Summarize the current state of research and limitations in the field of AI in kidney transplant pathology diagnostics and provide a future outlook.

MATERIALS AND METHODS: Literature search in PubMed and Web of Science using the search terms "deep learning", "transplant", and "kidney". Based on these results and studies cited in the identified literature, a selection was made of studies that have a histopathological focus and use AI to improve kidney transplant diagnostics.

RESULTS AND CONCLUSION: Many studies have already made important contributions, particularly to the automation of the quantification of some histopathological lesions in nephropathology. This likely can be extended to automatically quantify all relevant lesions for a kidney transplant, such as Banff lesions. Important limitations and challenges exist in the collection of representative data sets and the updates of Banff classification, making large-scale studies challenging. The already positive study results make future AI support in kidney transplant pathology appear likely.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Pathologie (Heidelberg, Germany) - (2024) vom: 10. Apr.

Sprache:

Deutsch

Weiterer Titel:

Künstliche Intelligenz in der Nierentransplantationspathologie

Beteiligte Personen:

Bülow, Roman David [VerfasserIn]
Lan, Yu-Chia [VerfasserIn]
Amann, Kerstin [VerfasserIn]
Boor, Peter [VerfasserIn]

Links:

Volltext

Themen:

Computer assistance
Datenintegration
Deep learning
English Abstract
Histomorphometry
Journal Article
Kidney transplantation
Review

Anmerkungen:

Date Revised 10.04.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1007/s00292-024-01324-7

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370874285