No need to "sugar coat" : Removing glycocalyx on apoptotic blebs promotes phagocytosis
Copyright © 2024 Elsevier Inc. All rights reserved..
The viscous glycocalyx of mammalian cells, composed of glucosaminoglycans, glycolipids, and glycoproteins, "sugar coat" the outer plasma membrane. In this issue of Developmental Cell, Le et al. (2024) show that the glycocalyx is removed from apoptotic blebs via disassembly of the cortical cytoskeleton, exposing the "eat-me" signals necessary for efferocytosis.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:59 |
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| Enthalten in: |
Developmental cell - 59(2024), 7 vom: 08. Apr., Seite 827-829 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kelley, Shannon M [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 11.04.2024 Date Revised 19.04.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.1016/j.devcel.2024.02.014 |
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| Förderinstitution / Projekttitel: |
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| 520 | |a The viscous glycocalyx of mammalian cells, composed of glucosaminoglycans, glycolipids, and glycoproteins, "sugar coat" the outer plasma membrane. In this issue of Developmental Cell, Le et al. (2024) show that the glycocalyx is removed from apoptotic blebs via disassembly of the cortical cytoskeleton, exposing the "eat-me" signals necessary for efferocytosis | ||
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