FEN1-assisted DNA logic amplifier circuit for fast and compact DNA computing
This work developed DNA amplifier logic gates (AND-OR, OR-AND, FAN-IN, FAN-OUT, and 4-bit square-root circuits) using a flap endonuclease 1 (FEN1)-catalyzed signal amplification reaction, for the fastest and compact DNA computing. Moreover, the logic circuit can use input strands with concentrations of less than 1 nM, which is more than 100 times lower than the input concentration of other DNA logic circuits, providing a promising methodology for constructing fast and compact DNA computations.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:60 |
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| Enthalten in: |
Chemical communications (Cambridge, England) - 60(2024), 34 vom: 23. Apr., Seite 4593-4596 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Xiang, Zheng [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Revised 23.04.2024 published: Electronic Citation Status In-Process |
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| doi: |
10.1039/d4cc00203b |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM370672798 |
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| 100 | 1 | |a Xiang, Zheng |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a FEN1-assisted DNA logic amplifier circuit for fast and compact DNA computing |
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| 520 | |a This work developed DNA amplifier logic gates (AND-OR, OR-AND, FAN-IN, FAN-OUT, and 4-bit square-root circuits) using a flap endonuclease 1 (FEN1)-catalyzed signal amplification reaction, for the fastest and compact DNA computing. Moreover, the logic circuit can use input strands with concentrations of less than 1 nM, which is more than 100 times lower than the input concentration of other DNA logic circuits, providing a promising methodology for constructing fast and compact DNA computations | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Zheng, Jia-Yi |e verfasserin |4 aut | |
| 700 | 1 | |a Ma, Xueping |e verfasserin |4 aut | |
| 700 | 1 | |a Chu, Yanan |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Qinxin |e verfasserin |4 aut | |
| 700 | 1 | |a Zhou, Guohua |e verfasserin |4 aut | |
| 700 | 1 | |a Zou, Bingjie |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Haiping |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Chen |e verfasserin |4 aut | |
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| 773 | 1 | 8 | |g volume:60 |g year:2024 |g number:34 |g day:23 |g month:04 |g pages:4593-4596 |
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