Protective role of exercise on breast cancer-related osteoporosis in women undergoing aromatase inhibitors : A narrative review
© 2024 The Authors..
Hormone therapy following surgery reduces the risk of breast cancer (BC) recurrence and progression of hormone-sensitive BC, especially in postmenopausal women. Despite the antitumor efficacy of hormone therapy, particularly of aromatase inhibitors, they cause long-term side effects, mainly bone density reduction. Exercise can slow the rate of bone loss, which reduces the risk of fractures from osteoporosis, and could be an integrative treatment able to mitigate the BC treatment side effects positively impacting bone health. This narrative review aims to discuss studies on the effect of exercise on bone health in BC women undergoing aromatase inhibitors, highlighting the possible role of exercise as complementary to conventional therapies. Additionally, according to the literature revision, exercise practical applications to improve bone health in these patients are summarized.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
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| Enthalten in: |
Bone reports - 21(2024) vom: 26. Apr., Seite 101756 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cerulli, Claudia [VerfasserIn] |
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| Links: |
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| Themen: |
Aromatase inhibitors |
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| Anmerkungen: |
Date Revised 06.04.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.bonr.2024.101756 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Hormone therapy following surgery reduces the risk of breast cancer (BC) recurrence and progression of hormone-sensitive BC, especially in postmenopausal women. Despite the antitumor efficacy of hormone therapy, particularly of aromatase inhibitors, they cause long-term side effects, mainly bone density reduction. Exercise can slow the rate of bone loss, which reduces the risk of fractures from osteoporosis, and could be an integrative treatment able to mitigate the BC treatment side effects positively impacting bone health. This narrative review aims to discuss studies on the effect of exercise on bone health in BC women undergoing aromatase inhibitors, highlighting the possible role of exercise as complementary to conventional therapies. Additionally, according to the literature revision, exercise practical applications to improve bone health in these patients are summarized | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Aromatase inhibitors | |
| 650 | 4 | |a Breast cancer | |
| 650 | 4 | |a Osteoporosis prevention | |
| 650 | 4 | |a Physical exercise | |
| 650 | 4 | |a Treatment | |
| 700 | 1 | |a Moretti, Elisa |e verfasserin |4 aut | |
| 700 | 1 | |a Grazioli, Elisa |e verfasserin |4 aut | |
| 700 | 1 | |a Emerenziani, Gian Pietro |e verfasserin |4 aut | |
| 700 | 1 | |a Murri, Arianna |e verfasserin |4 aut | |
| 700 | 1 | |a Tranchita, Eliana |e verfasserin |4 aut | |
| 700 | 1 | |a Minganti, Carlo |e verfasserin |4 aut | |
| 700 | 1 | |a Di Cagno, Alessandra |e verfasserin |4 aut | |
| 700 | 1 | |a Parisi, Attilio |e verfasserin |4 aut | |
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