Efficacy and safety of mechanochemical ablation versus laser ablation in the treatment of primary great saphenous vein reflux : A randomized, open, parallel controlled clinical trial
OBJECTIVE: To evaluate the efficacy of a new mechanochemical ablation (MOCA) device versus endovenous laser ablation (EVLA) for primary great saphenous vein (GSV) reflux.
MATERIALS AND METHODS: Prospectively analyze the demographics, treatment detail and outcomes data of 57 primary GSV reflux patients. Patients were randomly assigned to MOCA or EVLA group with random envelope method. Primary endpoint was 6-month closure rate of GSV. Secondary endpoint including technical success rate, the venous clinical severity score (VCSS), chronic venous insufficiency questionnaire (CIVIQ-20) score and visual analogue scale (VAS) for pain.
RESULTS: The procedures were well tolerated according to the VAS score. The 6-month closure rate was 85.71% in MOCA and 96.55% in EVLA group (p = .194). Significant changes were observed in regard of VCSS and CIVIQ-20 score at 6-month follow-up. Skin paresthesia occurred in 0 in MOCA and 5 in EVLA group.
CONCLUSION: The new MOCA device is safe and effective in treating primary great saphenous vein reflux. The 6-month closure rate is non-inferior compared with EVLA. However, the long-term results need further follow-up.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Vascular - (2024) vom: 01. Apr., Seite 17085381241244865 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chen, Jie [VerfasserIn] |
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| Links: |
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| Themen: |
Endovenous laser ablation |
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| Anmerkungen: |
Date Revised 02.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1177/17085381241244865 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM370515277 |
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| 100 | 1 | |a Chen, Jie |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Efficacy and safety of mechanochemical ablation versus laser ablation in the treatment of primary great saphenous vein reflux |b A randomized, open, parallel controlled clinical trial |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Revised 02.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a OBJECTIVE: To evaluate the efficacy of a new mechanochemical ablation (MOCA) device versus endovenous laser ablation (EVLA) for primary great saphenous vein (GSV) reflux | ||
| 520 | |a MATERIALS AND METHODS: Prospectively analyze the demographics, treatment detail and outcomes data of 57 primary GSV reflux patients. Patients were randomly assigned to MOCA or EVLA group with random envelope method. Primary endpoint was 6-month closure rate of GSV. Secondary endpoint including technical success rate, the venous clinical severity score (VCSS), chronic venous insufficiency questionnaire (CIVIQ-20) score and visual analogue scale (VAS) for pain | ||
| 520 | |a RESULTS: The procedures were well tolerated according to the VAS score. The 6-month closure rate was 85.71% in MOCA and 96.55% in EVLA group (p = .194). Significant changes were observed in regard of VCSS and CIVIQ-20 score at 6-month follow-up. Skin paresthesia occurred in 0 in MOCA and 5 in EVLA group | ||
| 520 | |a CONCLUSION: The new MOCA device is safe and effective in treating primary great saphenous vein reflux. The 6-month closure rate is non-inferior compared with EVLA. However, the long-term results need further follow-up | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Primary great saphenous vein reflux | |
| 650 | 4 | |a endovenous laser ablation | |
| 650 | 4 | |a mechanochemical ablation | |
| 700 | 1 | |a Zhang, Jianbin |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Qian |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Shu |e verfasserin |4 aut | |
| 700 | 1 | |a Sun, Mingsheng |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Peng |e verfasserin |4 aut | |
| 700 | 1 | |a Ye, Zhidong |e verfasserin |4 aut | |
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