Trends in prenatal prescription opioid use among Medicaid beneficiaries in Wisconsin, 2010-2019
© 2024. The Author(s), under exclusive licence to Springer Nature America, Inc..
OBJECTIVE: To examine changes in prenatal opioid prescription exposure following new guidelines and policies.
STUDY DESIGN: Cohort study of all (262,284) Wisconsin Medicaid-insured live births 2010-2019. Prenatal exposures were classified as analgesic, short term, and chronic (90+ days), and medications used to treat opioid use disorder (MOUD). We describe overall and stratified temporal trends and used linear probability models with interaction terms to test their significance.
RESULT: We found 42,437 (16.2%) infants with prenatal exposure; most (90.5%) reflected analgesic opioids. From 2010 to 2019, overall exposure declined 12.8 percentage points (95% CI = 12.1-13.1). Reductions were observed across maternal demographic groups and in both rural and urban settings, though the extent varied. There was a small reduction in chronic analgesic exposure and a concurrent increase in MOUD.
CONCLUSION: Broad and sustained declines in prenatal prescription opioid exposure occurred over the decade, with little change in the percentage of infants chronically exposed.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Journal of perinatology : official journal of the California Perinatal Association - (2024) vom: 01. Apr. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ehrenthal, Deborah B [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Revised 06.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1038/s41372-024-01954-y |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM370508939 |
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| 500 | |a published: Print-Electronic | ||
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| 520 | |a © 2024. The Author(s), under exclusive licence to Springer Nature America, Inc. | ||
| 520 | |a OBJECTIVE: To examine changes in prenatal opioid prescription exposure following new guidelines and policies | ||
| 520 | |a STUDY DESIGN: Cohort study of all (262,284) Wisconsin Medicaid-insured live births 2010-2019. Prenatal exposures were classified as analgesic, short term, and chronic (90+ days), and medications used to treat opioid use disorder (MOUD). We describe overall and stratified temporal trends and used linear probability models with interaction terms to test their significance | ||
| 520 | |a RESULT: We found 42,437 (16.2%) infants with prenatal exposure; most (90.5%) reflected analgesic opioids. From 2010 to 2019, overall exposure declined 12.8 percentage points (95% CI = 12.1-13.1). Reductions were observed across maternal demographic groups and in both rural and urban settings, though the extent varied. There was a small reduction in chronic analgesic exposure and a concurrent increase in MOUD | ||
| 520 | |a CONCLUSION: Broad and sustained declines in prenatal prescription opioid exposure occurred over the decade, with little change in the percentage of infants chronically exposed | ||
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| 700 | 1 | |a Kirby, Russell S |e verfasserin |4 aut | |
| 700 | 1 | |a Berger, Lawrence M |e verfasserin |4 aut | |
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