Poor rhinitis and asthma control is associated with decreased health-related quality-of-life and utilities : A MASK-air study
Copyright © 2024. Published by Elsevier Inc..
BACKGROUND: Allergic rhinitis (AR) and asthma may impact health-related quality-of-life. However, national estimates on the quality-of-life of patients with AR or asthma are lacking.
OBJECTIVE: To provide estimates for utility scores and EQ-5D Visual Analog Scale (VAS) for patients with AR or asthma.
METHODS: We conducted a cross-sectional study using direct patient data from the MASK-air® app on European MASK-air® users with self-reported AR or asthma. We used a multiattribute instrument (EQ-5D) to measure quality-of-life (as utility scores and EQ-5D VAS values). Mean scores were calculated per country and disease control level using multilevel regression models with post-stratification, accounting for age and sex biases.
RESULTS: We assessed data from up to 7905 MASK-air® users reporting a total of up to 82,737 days. For AR, utilities ranged from 0.86-0.99 for good control versus 0.72-0.85 for poor control; EQ-5D VAS levels ranged from 78.9-87.9 for good control versus 55.3-64.2 for poor control. For asthma, utilities ranged from 0.84-0.97 for good control versus 0.73-0.87 for poor control; EQ-5D VAS levels ranged from 68.4-81.5 for good control versus 51.4-64.2 for poor control. Poor disease control was associated with a mean loss of 0.14 utilities for both AR and asthma. For the same control levels, AR and asthma were associated with similar utilities and EQ-5D VAS levels. However, lower values were observed for asthma+AR when compared to AR alone.
CONCLUSION: Poor AR or asthma control are associated with reduced quality-of-life. The estimates obtained from mHealth data may provide valuable insights for health technology assessment studies.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
The journal of allergy and clinical immunology. In practice - (2024) vom: 30. März |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Vieira, Rafael José [VerfasserIn] |
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| Links: |
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| Themen: |
Allergic rhinitis |
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| Anmerkungen: |
Date Revised 01.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.jaip.2024.03.036 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM370506383 |
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| 041 | |a eng | ||
| 100 | 1 | |a Vieira, Rafael José |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Poor rhinitis and asthma control is associated with decreased health-related quality-of-life and utilities |b A MASK-air study |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Revised 01.04.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a Copyright © 2024. Published by Elsevier Inc. | ||
| 520 | |a BACKGROUND: Allergic rhinitis (AR) and asthma may impact health-related quality-of-life. However, national estimates on the quality-of-life of patients with AR or asthma are lacking | ||
| 520 | |a OBJECTIVE: To provide estimates for utility scores and EQ-5D Visual Analog Scale (VAS) for patients with AR or asthma | ||
| 520 | |a METHODS: We conducted a cross-sectional study using direct patient data from the MASK-air® app on European MASK-air® users with self-reported AR or asthma. We used a multiattribute instrument (EQ-5D) to measure quality-of-life (as utility scores and EQ-5D VAS values). Mean scores were calculated per country and disease control level using multilevel regression models with post-stratification, accounting for age and sex biases | ||
| 520 | |a RESULTS: We assessed data from up to 7905 MASK-air® users reporting a total of up to 82,737 days. For AR, utilities ranged from 0.86-0.99 for good control versus 0.72-0.85 for poor control; EQ-5D VAS levels ranged from 78.9-87.9 for good control versus 55.3-64.2 for poor control. For asthma, utilities ranged from 0.84-0.97 for good control versus 0.73-0.87 for poor control; EQ-5D VAS levels ranged from 68.4-81.5 for good control versus 51.4-64.2 for poor control. Poor disease control was associated with a mean loss of 0.14 utilities for both AR and asthma. For the same control levels, AR and asthma were associated with similar utilities and EQ-5D VAS levels. However, lower values were observed for asthma+AR when compared to AR alone | ||
| 520 | |a CONCLUSION: Poor AR or asthma control are associated with reduced quality-of-life. The estimates obtained from mHealth data may provide valuable insights for health technology assessment studies | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Allergic rhinitis | |
| 650 | 4 | |a Asthma | |
| 650 | 4 | |a EQ-5D-5L | |
| 650 | 4 | |a Health-related quality of life | |
| 650 | 4 | |a Mobile health | |
| 650 | 4 | |a Quality of life | |
| 650 | 4 | |a Real-world data | |
| 650 | 4 | |a Utilities | |
| 700 | 1 | |a Leemann, Lucas |e verfasserin |4 aut | |
| 700 | 1 | |a Briggs, Andrew |e verfasserin |4 aut | |
| 700 | 1 | |a Pereira, Ana Margarida |e verfasserin |4 aut | |
| 700 | 1 | |a Savouré, Marine |e verfasserin |4 aut | |
| 700 | 1 | |a Kuna, Piotr |e verfasserin |4 aut | |
| 700 | 1 | |a Morais-Almeida, Mário |e verfasserin |4 aut | |
| 700 | 1 | |a Bewick, Michael |e verfasserin |4 aut | |
| 700 | 1 | |a Azevedo, Luís Filipe |e verfasserin |4 aut | |
| 700 | 1 | |a Louis, Renaud |e verfasserin |4 aut | |
| 700 | 1 | |a Klimek, Ludger |e verfasserin |4 aut | |
| 700 | 1 | |a Bahbah, Farah |e verfasserin |4 aut | |
| 700 | 1 | |a Samolinski, Boleslaw |e verfasserin |4 aut | |
| 700 | 1 | |a Anto, Josep M |e verfasserin |4 aut | |
| 700 | 1 | |a Zuberbier, Torsten |e verfasserin |4 aut | |
| 700 | 1 | |a Fonseca, João A |e verfasserin |4 aut | |
| 700 | 1 | |a Bousquet, Jean |e verfasserin |4 aut | |
| 700 | 1 | |a Sousa-Pinto, Bernardo |e verfasserin |4 aut | |
| 700 | 0 | |a MASK-air think tank |e verfasserin |4 aut | |
| 700 | 1 | |a Czarlewski, Wienczyslawa |e investigator |4 oth | |
| 700 | 1 | |a Bedbrook, Anna |e investigator |4 oth | |
| 700 | 1 | |a Haahtela, Tari |e investigator |4 oth | |
| 700 | 1 | |a Canonica, G Walter |e investigator |4 oth | |
| 700 | 1 | |a Costa, Elisio M |e investigator |4 oth | |
| 700 | 1 | |a Kupczyk, Maciej |e investigator |4 oth | |
| 700 | 1 | |a Kvedariene, Violeta |e investigator |4 oth | |
| 700 | 1 | |a Kulus, Marek |e investigator |4 oth | |
| 700 | 1 | |a Larenas-Linnemann, Désirée E |e investigator |4 oth | |
| 700 | 1 | |a Pfaar, Oliver |e investigator |4 oth | |
| 700 | 1 | |a Papadopoulos, Nikolaos G |e investigator |4 oth | |
| 700 | 1 | |a Pham-Thi, Nhân |e investigator |4 oth | |
| 700 | 1 | |a Regateiro, Frederico S |e investigator |4 oth | |
| 700 | 1 | |a Roche, Nicolas |e investigator |4 oth | |
| 700 | 1 | |a Sastre, Joaquin |e investigator |4 oth | |
| 700 | 1 | |a Scichilone, Nicola |e investigator |4 oth | |
| 700 | 1 | |a Taborda-Barata, Luis |e investigator |4 oth | |
| 700 | 1 | |a Valiulis, Arunas |e investigator |4 oth | |
| 700 | 1 | |a Yorgancioglu, Arzu |e investigator |4 oth | |
| 700 | 1 | |a Ventura, Maria Teresa |e investigator |4 oth | |
| 700 | 1 | |a Almeida, Rute |e investigator |4 oth | |
| 700 | 1 | |a Amaral, Rita |e investigator |4 oth | |
| 700 | 1 | |a Ansotegui, Ignacio J |e investigator |4 oth | |
| 700 | 1 | |a Bergmann, Karl C |e investigator |4 oth | |
| 700 | 1 | |a Bosnic-Anticevich, Sinthia |e investigator |4 oth | |
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| 700 | 1 | |a Cardona, Victoria |e investigator |4 oth | |
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| 700 | 1 | |a Loureiro, Claudia Chaves |e investigator |4 oth | |
| 700 | 1 | |a Cingi, Cemal |e investigator |4 oth | |
| 700 | 1 | |a Cruz, Alvaro A |e investigator |4 oth | |
| 700 | 1 | |a Fokkens, Wytske J |e investigator |4 oth | |
| 700 | 1 | |a de Vries, Govert |e investigator |4 oth | |
| 700 | 1 | |a Gemicioglu, Bilun |e investigator |4 oth | |
| 700 | 1 | |a Giuliana, Antonio Fm |e investigator |4 oth | |
| 700 | 1 | |a Linuma, Tomohisa |e investigator |4 oth | |
| 700 | 1 | |a Ivancevich, Juan Carlos |e investigator |4 oth | |
| 700 | 1 | |a Jácome, Cristina |e investigator |4 oth | |
| 700 | 1 | |a Kaidashev, Igor |e investigator |4 oth | |
| 700 | 1 | |a Kraxner, Helga |e investigator |4 oth | |
| 700 | 1 | |a Laune, Daniel |e investigator |4 oth | |
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