Lupus nephritis presenting with massive ascites and pleural effusion (pseudo-pseudo Meigs' syndrome)
Copyright © 2024 by The Korean College of Rheumatology. All rights reserved..
The triad of ascites, pleural effusion, and elevated cancer antigen-125 (CA-125) levels in the absence of ovarian malignancy in systemic lupus erythematosus patients is specifically named pseudo-pseudo Meigs' syndrome (PPMS) or Tjalma syndrome. In this case we reported a 33 years female patient with pleural effusion lasting for 3 years and new onset progressive massive ascites and increased level of CA-125. After she was evaluated for an underlying benign and malign ovarian tumor or any other malignancies, serologic tests were requested with respect to progressive renal dysfunction, proteinuria, lymphopenia, anemia, and effusion. She was diagnosed with systemic lupus erythamatosus (SLE) and renal biopsy showed class-V lupus nephritis. Immunosuppressive treatment led to improvement in both SLE activity and components of PPMS, including massive ascites and pleural effusion and without the need of diuretics. Co-existence of unexplained CA-125 increase, pleural effusion, and ascites might be related to PPMS and detailed examination to exclude malignancy and early and effective treatment of SLE are the mainstay of management.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:31 |
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| Enthalten in: |
Journal of rheumatic diseases - 31(2024), 2 vom: 01. Apr., Seite 116-119 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Deniz, Rabia [VerfasserIn] |
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| Anmerkungen: |
Date Revised 03.04.2024 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.4078/jrd.2023.0052 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM370493044 |
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| 245 | 1 | 0 | |a Lupus nephritis presenting with massive ascites and pleural effusion (pseudo-pseudo Meigs' syndrome) |
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| 520 | |a Copyright © 2024 by The Korean College of Rheumatology. All rights reserved. | ||
| 520 | |a The triad of ascites, pleural effusion, and elevated cancer antigen-125 (CA-125) levels in the absence of ovarian malignancy in systemic lupus erythematosus patients is specifically named pseudo-pseudo Meigs' syndrome (PPMS) or Tjalma syndrome. In this case we reported a 33 years female patient with pleural effusion lasting for 3 years and new onset progressive massive ascites and increased level of CA-125. After she was evaluated for an underlying benign and malign ovarian tumor or any other malignancies, serologic tests were requested with respect to progressive renal dysfunction, proteinuria, lymphopenia, anemia, and effusion. She was diagnosed with systemic lupus erythamatosus (SLE) and renal biopsy showed class-V lupus nephritis. Immunosuppressive treatment led to improvement in both SLE activity and components of PPMS, including massive ascites and pleural effusion and without the need of diuretics. Co-existence of unexplained CA-125 increase, pleural effusion, and ascites might be related to PPMS and detailed examination to exclude malignancy and early and effective treatment of SLE are the mainstay of management | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Lupus nephritis | |
| 650 | 4 | |a Systemic lupus erythematosus | |
| 700 | 1 | |a Hacımurtazaoğlu-Demir, Gülşah |e verfasserin |4 aut | |
| 700 | 1 | |a Karaalioğlu, Bilgin |e verfasserin |4 aut | |
| 700 | 1 | |a Özgür, Duygu Sevinç |e verfasserin |4 aut | |
| 700 | 1 | |a Akkuzu, Gamze |e verfasserin |4 aut | |
| 700 | 1 | |a Yıldırım, Fatih |e verfasserin |4 aut | |
| 700 | 1 | |a Bes, Cemal |e verfasserin |4 aut | |
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