Micronized acellular dermal matrix combined with platelet rich plasma in the treatment of atrophic acne scars : A self-controlled split face study
© 2024 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC..
BACKGROUND: Micronized acellular dermal matrix (mADM) can induce tissue regeneration and repair, and filling.
OBJECTIVES: The efficacy and safety of (mADM) were evaluated in the treatment of atrophic acne scar.
METHODS: In this single-blinded, self-controlled, split-face study, 16 patients (48 scar sites) were divided into treatment group (24 scar sites) and control group (24 scar sites). One side of the affected area was treated with mADM combined with platelet rich plasma (PRP) injection as the treatment group; the other side of the affected area was treated with PRP injection as the control group. The efficacy was evaluated by the Acne scar assessment scale (ASAS) and Acne Scar Weight Rating Scale (ECCA) 3 months after treatment.
RESULTS: After 3-month treatment in 16 patients, the atrophic acne scars in both groups were all improved. The ASAS score and ECCA weight score in the treatment group was significantly lower than that in the control group (2.50 ± 0.51 vs. 3.62 ± 0.77 and 14.17 ± 10.18 vs. 31.88 ± 13.25; p < 0.001).
LIMITATIONS: Short-term 3-month treatment period. Small sample size limits generalizability of results.
CONCLUSION: The curative effect of mADM combined with PRP is significantly better than that of PRP alone.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Journal of cosmetic dermatology - (2024) vom: 01. Apr. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Park, Sunwoo [VerfasserIn] |
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| Links: |
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| Themen: |
Atrophic acne scar |
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| Anmerkungen: |
Date Revised 01.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1111/jocd.16293 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM370478622 |
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| 500 | |a published: Print-Electronic | ||
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| 520 | |a © 2024 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC. | ||
| 520 | |a BACKGROUND: Micronized acellular dermal matrix (mADM) can induce tissue regeneration and repair, and filling | ||
| 520 | |a OBJECTIVES: The efficacy and safety of (mADM) were evaluated in the treatment of atrophic acne scar | ||
| 520 | |a METHODS: In this single-blinded, self-controlled, split-face study, 16 patients (48 scar sites) were divided into treatment group (24 scar sites) and control group (24 scar sites). One side of the affected area was treated with mADM combined with platelet rich plasma (PRP) injection as the treatment group; the other side of the affected area was treated with PRP injection as the control group. The efficacy was evaluated by the Acne scar assessment scale (ASAS) and Acne Scar Weight Rating Scale (ECCA) 3 months after treatment | ||
| 520 | |a RESULTS: After 3-month treatment in 16 patients, the atrophic acne scars in both groups were all improved. The ASAS score and ECCA weight score in the treatment group was significantly lower than that in the control group (2.50 ± 0.51 vs. 3.62 ± 0.77 and 14.17 ± 10.18 vs. 31.88 ± 13.25; p < 0.001) | ||
| 520 | |a LIMITATIONS: Short-term 3-month treatment period. Small sample size limits generalizability of results | ||
| 520 | |a CONCLUSION: The curative effect of mADM combined with PRP is significantly better than that of PRP alone | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a atrophic acne scar | |
| 650 | 4 | |a boxcar scar | |
| 650 | 4 | |a micronized acellular dermal matrix | |
| 650 | 4 | |a platelet rich plasma | |
| 650 | 4 | |a rolling scar | |
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| 700 | 1 | |a Ao, Xian |e verfasserin |4 aut | |
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| 700 | 1 | |a Li, Guomin |e verfasserin |4 aut | |
| 700 | 1 | |a Xian, Hua |e verfasserin |4 aut | |
| 700 | 1 | |a Du, Meiyi |e verfasserin |4 aut | |
| 700 | 1 | |a Xue, Ruzeng |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Chunmei |e verfasserin |4 aut | |
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