Double lung transplantation is better than single lung transplantation for end-stage chronic obstructive pulmonary disease : a meta-analysis

© 2024. The Author(s)..

BACKGROUND: Lung transplantation is one of the most common treatment options for patients with end-stage chronic obstructive pulmonary disease. However, the choice between single and double lung transplantation for these patients remains a matter of debate. Therefore, we performed a systematic search of medical databases for studies on single lung transplantation, double lung transplantation, and chronic obstructive pulmonary disease.

METHODS: The rate ratio and hazard ratio of survival were analyzed. The meta-analysis included 15 case-control and retrospective registry studies.

RESULTS: The rate ratios of the 3-year survival (0.937 and P = 0.041) and 5-year survival (0.775 and P = 0.000) were lower for single lung transplantation than for double lung transplantation. However, the hazard ratio did not differ significantly between the two.

CONCLUSIONS: Double lung transplantation was found to provide better benefits than single lung transplantation in terms of the long-term survival in patients with chronic obstructive pulmonary disease.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:19

Enthalten in:

Journal of cardiothoracic surgery - 19(2024), 1 vom: 30. März, Seite 162

Sprache:

Englisch

Beteiligte Personen:

Fang, Yu-Chi [VerfasserIn]
Cheng, Wen-Hsin [VerfasserIn]
Lu, Hung-I [VerfasserIn]
Wang, Yi-Shi [VerfasserIn]
Chuang, Kai-Hao [VerfasserIn]
Lai, Hsing-Hua [VerfasserIn]
Chen, Yu [VerfasserIn]
Chen, Li-Chun [VerfasserIn]
Tsai, Meng-Yun [VerfasserIn]
Chang, Yu-Ping [VerfasserIn]
Huang, Kuo-Tung [VerfasserIn]
Lo, Chien-Ming [VerfasserIn]

Links:

Volltext

Themen:

Chronic obstructive
Journal Article
Lung transplantation
Meta-Analysis
Meta-analysis
Proportional hazards models
Pulmonary disease
Registries
Survival

Anmerkungen:

Date Completed 01.04.2024

Date Revised 02.04.2024

published: Electronic

Citation Status MEDLINE

doi:

10.1186/s13019-024-02654-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370449746