The impact of existing total anti-toxin B IgG immunity in outcomes of recurrent Clostridioides difficile infection
Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved..
Late anti-toxin-B humoral immunity acquired after treatment is important for preventing recurrent Clostridioides difficile infection. We prospectively-measured anti-toxin-B IgG and neutralization titers at diagnosis as potential early predictors of recurrence. High anti-toxin-B-IgG/neutralizing antibodies were associated with short-lasting protection within 6-weeks, however, no difference in recurrence risk was observed by 90-days post-infection.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:87 |
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| Enthalten in: |
Anaerobe - 87(2024) vom: 28. März, Seite 102842 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Rigo, Isaura [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-toxin B IgG antibodies |
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| Anmerkungen: |
Date Revised 16.04.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.anaerobe.2024.102842 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Late anti-toxin-B humoral immunity acquired after treatment is important for preventing recurrent Clostridioides difficile infection. We prospectively-measured anti-toxin-B IgG and neutralization titers at diagnosis as potential early predictors of recurrence. High anti-toxin-B-IgG/neutralizing antibodies were associated with short-lasting protection within 6-weeks, however, no difference in recurrence risk was observed by 90-days post-infection | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a C. difficile infection (CDI) | |
| 650 | 4 | |a Neutralizing antibodies | |
| 650 | 4 | |a anti-toxin B IgG antibodies | |
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| 700 | 1 | |a Ramakrishnan, Girija |e verfasserin |4 aut | |
| 700 | 1 | |a Naz, Farha |e verfasserin |4 aut | |
| 700 | 1 | |a Madden, Gregory R |e verfasserin |4 aut | |
| 700 | 1 | |a Petri, William A |e verfasserin |4 aut | |
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