Nano-Innovations in Cancer Therapy : The Unparalleled Potential of MXene Conjugates

MXenes are two-dimensional transition metal carbides, nitrides, and carbonitrides that have become important materials in nanotechnology because of their remarkable mechanical, electrical, and thermal characteristics. This review emphasizes how crucial MXene conjugates are for several biomedical applications, especially in the field of cancer. These two-dimensional (2D) nanoconjugates with photothermal, chemotherapeutic, and photodynamic activities have demonstrated promise for highly effective and noninvasive anticancer therapy. MXene conjugates, with their distinctive optical capabilities, have been employed for bioimaging and biosensing, and their excellent light-to-heat conversion efficiency makes them perfect biocompatible and notably proficient nanoscale agents for photothermal applications. The synthesis and characterization of MXenes provide a framework for an in-depth understanding of various fabrication techniques and their importance in the customized formation of MXene conjugates. The following sections explore MXene-based conjugates for nanotheranostics and demonstrate their enormous potential for biomedical applications. Nanoconjugates, such as polymers, metals, graphene, hydrogels, biomimetics, quantum dots, and radio conjugates, exhibit unique properties that can be used for various therapeutic and diagnostic applications in the field of cancer nanotheranostics. An additional layer of understanding into the safety concerns of MXene nanoconjugates is provided by detailing their toxicity viewpoints. Furthermore, the review concludes by addressing the opportunities and challenges in the clinical translation of MXene-based nanoconjugates, emphasizing their potential in real-world medical practices.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:17

Enthalten in:

Materials (Basel, Switzerland) - 17(2024), 6 vom: 20. März

Sprache:

Englisch

Beteiligte Personen:

Kulkarni, Sanjay [VerfasserIn]
Soman, Soji [VerfasserIn]
Navti, Prerana D [VerfasserIn]
Roy, Amrita Arup [VerfasserIn]
Nikam, Ajinkya Nitin [VerfasserIn]
Vineeth, P [VerfasserIn]
Kulkarni, Jahnavi [VerfasserIn]
Shirur, Krishnaraj Somayaji [VerfasserIn]
Pandey, Abhijeet [VerfasserIn]
George, Sajan D [VerfasserIn]
Mutalik, Srinivas [VerfasserIn]

Links:

Volltext

Themen:

2D materials
Cancer
Conjugates
Journal Article
MXene
Nanotheranostics
Review

Anmerkungen:

Date Revised 30.03.2024

published: Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.3390/ma17061423

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370311221