Short- and Long-term Outcomes After Colonic Stent Insertion as a Bridge to Surgery in Elderly Colorectal Cancer Patients
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved..
BACKGROUND/AIM: Colonic stents have been inserted as a bridge to surgery in patients with resectable colorectal cancer, allowing bowel decompression for systemic assessment and better preparation to avoid stoma construction. However, reports of short- and long-term prognoses for elderly patients remain limited.
PATIENTS AND METHODS: This retrospective study reviewed 175 consecutive patients who underwent colonic stent insertion for bowel obstruction followed by curative colectomy. Patients were divided into those >80 years old (Old, n=49) and those <80 years old (Young, n=126). After propensity score matching, 41 patients in each group matched.
RESULTS: Before matching, performance status was poorer (p<0.001), postoperative complication rate was higher (p=0.009), adjuvant chemotherapy rate was lower (p<0.001), and hospital stay was longer (p<0.001) in the Old group. After matching, adjuvant chemotherapy rate was lower (9.8% vs. 39.0%; p=0.003) and hospital stay was longer (14 vs. 12 days; p=0.029) in the Old group. Five-year relapse-free survival (42.9% vs. 68.8%; p=0.200), overall survival (66.3% vs. 87.7%; p=0.081), and cancer-specific survival (68.2% vs. 87.7%; p=0.129) rates were comparable between groups.
CONCLUSION: Colorectal resection after colonic stent insertion is useful for elderly patients, with potential to reduce postoperative complication rates and achieve good long-term results with appropriate case selection.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:44 |
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| Enthalten in: |
Anticancer research - 44(2024), 4 vom: 27. März, Seite 1637-1643 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Shiraishi, Toshio [VerfasserIn] |
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| Anmerkungen: |
Date Completed 29.03.2024 Date Revised 29.03.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.21873/anticanres.16962 |
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| Förderinstitution / Projekttitel: |
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NLM370275217 |
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| 520 | |a Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved. | ||
| 520 | |a BACKGROUND/AIM: Colonic stents have been inserted as a bridge to surgery in patients with resectable colorectal cancer, allowing bowel decompression for systemic assessment and better preparation to avoid stoma construction. However, reports of short- and long-term prognoses for elderly patients remain limited | ||
| 520 | |a PATIENTS AND METHODS: This retrospective study reviewed 175 consecutive patients who underwent colonic stent insertion for bowel obstruction followed by curative colectomy. Patients were divided into those >80 years old (Old, n=49) and those <80 years old (Young, n=126). After propensity score matching, 41 patients in each group matched | ||
| 520 | |a RESULTS: Before matching, performance status was poorer (p<0.001), postoperative complication rate was higher (p=0.009), adjuvant chemotherapy rate was lower (p<0.001), and hospital stay was longer (p<0.001) in the Old group. After matching, adjuvant chemotherapy rate was lower (9.8% vs. 39.0%; p=0.003) and hospital stay was longer (14 vs. 12 days; p=0.029) in the Old group. Five-year relapse-free survival (42.9% vs. 68.8%; p=0.200), overall survival (66.3% vs. 87.7%; p=0.081), and cancer-specific survival (68.2% vs. 87.7%; p=0.129) rates were comparable between groups | ||
| 520 | |a CONCLUSION: Colorectal resection after colonic stent insertion is useful for elderly patients, with potential to reduce postoperative complication rates and achieve good long-term results with appropriate case selection | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Colonic stent | |
| 650 | 4 | |a elderly patient | |
| 650 | 4 | |a prognosis | |
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| 700 | 1 | |a Ono, Rika |e verfasserin |4 aut | |
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| 700 | 1 | |a Hashimoto, Shintaro |e verfasserin |4 aut | |
| 700 | 1 | |a Oishi, Kaido |e verfasserin |4 aut | |
| 700 | 1 | |a Takamura, Yuma |e verfasserin |4 aut | |
| 700 | 1 | |a Nonaka, Takashi |e verfasserin |4 aut | |
| 700 | 1 | |a Hisanaga, Makoto |e verfasserin |4 aut | |
| 700 | 1 | |a Ishii, Mitsutoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Takeshita, Hiroaki |e verfasserin |4 aut | |
| 700 | 1 | |a To, Kazuo |e verfasserin |4 aut | |
| 700 | 1 | |a Ishimaru, Kazuhide |e verfasserin |4 aut | |
| 700 | 1 | |a Sawai, Terumitsu |e verfasserin |4 aut | |
| 700 | 1 | |a Nagayasu, Takeshi |e verfasserin |4 aut | |
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