Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures
Osteoporotic fractures are induced by osteoporosis, which may lead to the degradation of bone tissues and microstructures and impair their healing ability. Conventional internal fixation therapies are ineffective in the treatment of osteoporotic fractures. Hence, developing tissue engineering materials is crucial for repairing osteoporotic fractures. It has been demonstrated that nanomaterials, particularly graphene oxide (GO), possess unique advantages in tissue engineering due to their excellent biocompatibility, mechanical properties, and osteoinductive abilities. Based on that, GO-nanocomposites have garnered significant attention and hold promising prospects for bone repair applications. This paper provides a comprehensive insight into the properties of GO, preparation methods for nanocomposites, advantages of these materials, and relevant mechanisms for osteoporotic fracture applications.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
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| Enthalten in: |
Nanomaterials (Basel, Switzerland) - 14(2024), 6 vom: 21. März |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zhou, Hongfa [VerfasserIn] |
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| Links: |
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| Themen: |
Graphene oxide |
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| Anmerkungen: |
Date Revised 30.03.2024 published: Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.3390/nano14060553 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM370252519 |
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| 520 | |a Osteoporotic fractures are induced by osteoporosis, which may lead to the degradation of bone tissues and microstructures and impair their healing ability. Conventional internal fixation therapies are ineffective in the treatment of osteoporotic fractures. Hence, developing tissue engineering materials is crucial for repairing osteoporotic fractures. It has been demonstrated that nanomaterials, particularly graphene oxide (GO), possess unique advantages in tissue engineering due to their excellent biocompatibility, mechanical properties, and osteoinductive abilities. Based on that, GO-nanocomposites have garnered significant attention and hold promising prospects for bone repair applications. This paper provides a comprehensive insight into the properties of GO, preparation methods for nanocomposites, advantages of these materials, and relevant mechanisms for osteoporotic fracture applications | ||
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| 700 | 1 | |a Zhang, Xuan |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, JingJing |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Jiayou |e verfasserin |4 aut | |
| 700 | 1 | |a Jia, Shicheng |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Deli |e verfasserin |4 aut | |
| 700 | 1 | |a Zeng, Hui |e verfasserin |4 aut | |
| 700 | 1 | |a Weng, Jian |e verfasserin |4 aut | |
| 700 | 1 | |a Yu, Fei |e verfasserin |4 aut | |
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