Developing a process to measure actual harm from medication errors in paediatric inpatients : From design to implementation
© 2024 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society..
AIMS: The potential harm associated with medication errors is widely reported, but data on actual harm are limited. When actual harm has been measured, assessment processes are often poorly described, limiting their ability to be reproduced by other studies. Our aim was to design and implement a new process to assess actual harm resulting from medication errors in paediatric inpatient care.
METHODS: Prescribing errors were identified through retrospective medical record reviews (n = 26 369 orders) and medication administration errors through direct observation (n = 5137 administrations) in a tertiary paediatric hospital. All errors were assigned potential harm severity ratings on a 5-point scale. Multidisciplinary panels reviewed case studies for patients assigned the highest three potential severity ratings and determined the following: actual harm occurrence and severity level, plausibility of a link between the error(s) and identified harm(s) and a confidence rating if no harm had occurred.
RESULTS: Multidisciplinary harm panels (n = 28) reviewed 566 case studies (173 prescribing related and 393 administration related) and found evidence of actual harm in 89 (prescribing = 22, administration = 67). Eight cases of serious harm cases were found (prescribing = 1, administration = 7) and no cases of severe harm. The panels were very confident in 65% of cases (n = 302) where no harm was found. Potential and actual harm ratings varied.
CONCLUSIONS: This harm assessment process provides a systematic method for determining actual harm from medication errors. The multidisciplinary nature of the panels was critical in evaluating specific clinical, therapeutic and contextual considerations including care delivery pathways, therapeutic dose ranges and drug-drug and drug-disease interactions.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2024 |
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Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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Enthalten in: |
British journal of clinical pharmacology - (2024) vom: 26. März |
Sprache: |
Englisch |
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Beteiligte Personen: |
Mumford, Virginia [VerfasserIn] |
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Links: |
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Date Revised 27.03.2024 published: Print-Electronic Citation Status Publisher |
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doi: |
10.1111/bcp.16052 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM370221893 |
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520 | |a © 2024 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society. | ||
520 | |a AIMS: The potential harm associated with medication errors is widely reported, but data on actual harm are limited. When actual harm has been measured, assessment processes are often poorly described, limiting their ability to be reproduced by other studies. Our aim was to design and implement a new process to assess actual harm resulting from medication errors in paediatric inpatient care | ||
520 | |a METHODS: Prescribing errors were identified through retrospective medical record reviews (n = 26 369 orders) and medication administration errors through direct observation (n = 5137 administrations) in a tertiary paediatric hospital. All errors were assigned potential harm severity ratings on a 5-point scale. Multidisciplinary panels reviewed case studies for patients assigned the highest three potential severity ratings and determined the following: actual harm occurrence and severity level, plausibility of a link between the error(s) and identified harm(s) and a confidence rating if no harm had occurred | ||
520 | |a RESULTS: Multidisciplinary harm panels (n = 28) reviewed 566 case studies (173 prescribing related and 393 administration related) and found evidence of actual harm in 89 (prescribing = 22, administration = 67). Eight cases of serious harm cases were found (prescribing = 1, administration = 7) and no cases of severe harm. The panels were very confident in 65% of cases (n = 302) where no harm was found. Potential and actual harm ratings varied | ||
520 | |a CONCLUSIONS: This harm assessment process provides a systematic method for determining actual harm from medication errors. The multidisciplinary nature of the panels was critical in evaluating specific clinical, therapeutic and contextual considerations including care delivery pathways, therapeutic dose ranges and drug-drug and drug-disease interactions | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a medication safety | |
650 | 4 | |a paediatrics | |
700 | 1 | |a Raban, Magdalena Z |e verfasserin |4 aut | |
700 | 1 | |a Li, Ling |e verfasserin |4 aut | |
700 | 1 | |a Fitzpatrick, Erin |e verfasserin |4 aut | |
700 | 1 | |a Woods, Amanda |e verfasserin |4 aut | |
700 | 1 | |a Merchant, Alison |e verfasserin |4 aut | |
700 | 1 | |a Badgery-Parker, Tim |e verfasserin |4 aut | |
700 | 1 | |a Gates, Peter |e verfasserin |4 aut | |
700 | 1 | |a Baysari, Melissa |e verfasserin |4 aut | |
700 | 1 | |a Day, Ric O |e verfasserin |4 aut | |
700 | 1 | |a Ambler, Geoffrey |e verfasserin |4 aut | |
700 | 1 | |a Dalla-Pozza, Luciano |e verfasserin |4 aut | |
700 | 1 | |a Gazarian, Madlen |e verfasserin |4 aut | |
700 | 1 | |a Gardo, Alan |e verfasserin |4 aut | |
700 | 1 | |a Barclay, Peter |e verfasserin |4 aut | |
700 | 1 | |a White, Les |e verfasserin |4 aut | |
700 | 1 | |a Westbrook, Johanna I |e verfasserin |4 aut | |
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