Mechanisms of medicinal, pharmaceutical, and immunomodulatory action of probiotics bacteria and their secondary metabolites against disease management : an overview

© 2024. Institute of Microbiology, Academy of Sciences of the Czech Republic, v.v.i..

Probiotics or bacteriotherapy is today's hot issue for public entities (Food and Agriculture Organization, and World Health Organization) as well as health and food industries since Metchnikoff and his colleagues hypothesized the correlation between probiotic consumption and human's health. They contribute to the newest and highly efficient arena of promising biotherapeutics. These are usually attractive in biomedical applications such as gut-related diseases like irritable bowel disease, diarrhea, gastrointestinal disorders, fungal infections, various allergies, parasitic and bacterial infections, viral diseases, and intestinal inflammation, and are also worth immunomodulation. The useful impact of probiotics is not limited to gut-related diseases alone. Still, these have proven benefits in various acute and chronic infectious diseases, like cancer, human immunodeficiency virus (HIV) diseases, and high serum cholesterol. Recently, different researchers have paid special attention to investigating biomedical applications of probiotics, but consolidated data regarding bacteriotherapy with a detailed mechanistically applied approach is scarce and controversial. The present article reviews the bio-interface of probiotic strains, mainly (i) why the demand for probiotics?, (ii) the current status of probiotics, (iii) an alternative to antibiotics, (iv) the potential applications towards disease management, (v) probiotics and industrialization, and (vi) futuristic approach.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - year:2024

Enthalten in:

Folia microbiologica - (2024) vom: 27. März

Sprache:

Englisch

Beteiligte Personen:

Nasreen, Sundas [VerfasserIn]
Ali, Shaukat [VerfasserIn]
Andleeb, Saiqa [VerfasserIn]
Summer, Muhammad [VerfasserIn]
Hussain, Tauqeer [VerfasserIn]
Imdad, Kaleem [VerfasserIn]
Ara, Chaman [VerfasserIn]
Tahir, Hafiz Muhammad [VerfasserIn]

Links:

Volltext

Themen:

Antibiotics
Bio-interface
Gut-associated diseases
Immunomodulation
Journal Article
Probiotics
Review

Anmerkungen:

Date Revised 27.03.2024

published: Print-Electronic

Citation Status Publisher

doi:

10.1007/s12223-024-01155-2

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370216040