Widefield, Swept-Source Optical Coherence Tomography Angiography Metrics as Predictors of Anti-VEGF Treatment in Retinal Vein Occlusions
BACKGROUND AND OBJECTIVE: Our objective was to assess baseline widefield swept-source optical coherence tomography angiography (WF SSOCTA) microvascular metrics as predictors for the number of anti-vascular endothelial growth factor (VEGF) injections and visual acuity (VA) at 12-months follow-up in patients with retinal vein occlusion (RVO).
PATIENTS AND METHODS: This was a prospective study including 49 RVO eyes from 49 patients who had not received an anti-VEGF injection for at least 3 months prior to imaging. Microvascular metrics from 6×6-mm and 12×12-mm angiograms were assessed using linear regression models, adjusting for age.
RESULTS: Reductions in the vessel density (VD) and vessel skeletonized density (VSD) vascular metrics were associated both with a higher number of anti-VEGF injections at all follow-up time points and reduced VA 12 months after imaging in all RVO eyes.
CONCLUSIONS: WF SS-OCTA VD and VSD micro-vascular metrics at baseline can prognosticate VA and number of anti-VEGF injections required at 3, 6, and 12 months in RVO eyes. [Ophthalmic Surg Lasers Imaging Retina 2024;55:xx-xx.].
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2024 |
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| Enthalten in: |
Ophthalmic surgery, lasers & imaging retina - (2024) vom: 01. März, Seite 1-9 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Finn, Matthew J [VerfasserIn] |
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| Anmerkungen: |
Date Revised 26.03.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.3928/23258160-20240208-02 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM37020557X |
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| 100 | 1 | |a Finn, Matthew J |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Widefield, Swept-Source Optical Coherence Tomography Angiography Metrics as Predictors of Anti-VEGF Treatment in Retinal Vein Occlusions |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Revised 26.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a BACKGROUND AND OBJECTIVE: Our objective was to assess baseline widefield swept-source optical coherence tomography angiography (WF SSOCTA) microvascular metrics as predictors for the number of anti-vascular endothelial growth factor (VEGF) injections and visual acuity (VA) at 12-months follow-up in patients with retinal vein occlusion (RVO) | ||
| 520 | |a PATIENTS AND METHODS: This was a prospective study including 49 RVO eyes from 49 patients who had not received an anti-VEGF injection for at least 3 months prior to imaging. Microvascular metrics from 6×6-mm and 12×12-mm angiograms were assessed using linear regression models, adjusting for age | ||
| 520 | |a RESULTS: Reductions in the vessel density (VD) and vessel skeletonized density (VSD) vascular metrics were associated both with a higher number of anti-VEGF injections at all follow-up time points and reduced VA 12 months after imaging in all RVO eyes | ||
| 520 | |a CONCLUSIONS: WF SS-OCTA VD and VSD micro-vascular metrics at baseline can prognosticate VA and number of anti-VEGF injections required at 3, 6, and 12 months in RVO eyes. [Ophthalmic Surg Lasers Imaging Retina 2024;55:xx-xx.] | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Baldwin, Grace |e verfasserin |4 aut | |
| 700 | 1 | |a Lains, Ines |e verfasserin |4 aut | |
| 700 | 1 | |a Garg, Itika |e verfasserin |4 aut | |
| 700 | 1 | |a Wescott, Hannah |e verfasserin |4 aut | |
| 700 | 1 | |a Vingopoulos, Filippos |e verfasserin |4 aut | |
| 700 | 1 | |a Zeng, Rebecca |e verfasserin |4 aut | |
| 700 | 1 | |a Choi, Hanna |e verfasserin |4 aut | |
| 700 | 1 | |a Tracy, Jack |e verfasserin |4 aut | |
| 700 | 1 | |a Razavi, Peyman |e verfasserin |4 aut | |
| 700 | 1 | |a Sayeh, Diane |e verfasserin |4 aut | |
| 700 | 1 | |a Patel, Nimesh A |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, David M |e verfasserin |4 aut | |
| 700 | 1 | |a Vavvas, Demetrios G |e verfasserin |4 aut | |
| 700 | 1 | |a Miller, John B |e verfasserin |4 aut | |
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