Modulation of Inflammatory Responses to Enhance Nerve Recovery after Spinal Cord Injury
© 2024. Korean Tissue Engineering and Regenerative Medicine Society..
Inflammation can occur at the wound site, and immune cells are necessary to trigger wound healing and tissue regeneration after injury. It is partly initiated by the rapid migration of immune cells such as neutrophils, inflammatory monocytes, and macrophages after spinal cord injury (SCI). Secondary inflammation can increase the wound area; thus, the function of tissues below the injury levels. Monocytes can differentiate into macrophages, and the macrophage phenotype can change from a pro-inflammatory phenotype to an anti-inflammatory phenotype. Therefore, various studies on immunomodulation have been performed to suppress secondary inflammation upon nerve damage. This editorial commentary focuses on various therapeutic methods that modulate inflammation and promote functional regeneration after SCI.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2024 |
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Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
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Enthalten in: |
Tissue engineering and regenerative medicine - 21(2024), 3 vom: 26. Apr., Seite 367-368 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Seo, Young-Kwon [VerfasserIn] |
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Links: |
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Themen: |
α-gal nanoparticles |
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Anmerkungen: |
Date Completed 03.04.2024 Date Revised 05.04.2024 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1007/s13770-024-00639-z |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM370201264 |
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520 | |a Inflammation can occur at the wound site, and immune cells are necessary to trigger wound healing and tissue regeneration after injury. It is partly initiated by the rapid migration of immune cells such as neutrophils, inflammatory monocytes, and macrophages after spinal cord injury (SCI). Secondary inflammation can increase the wound area; thus, the function of tissues below the injury levels. Monocytes can differentiate into macrophages, and the macrophage phenotype can change from a pro-inflammatory phenotype to an anti-inflammatory phenotype. Therefore, various studies on immunomodulation have been performed to suppress secondary inflammation upon nerve damage. This editorial commentary focuses on various therapeutic methods that modulate inflammation and promote functional regeneration after SCI | ||
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