Nanodiamonds : A Cutting-Edge Approach to Enhancing Biomedical Therapies and Diagnostics in Biosensing

© 2024 The Chemical Society of Japan & Wiley‐VCH GmbH..

Nanodiamonds (NDs) have garnered attention in the field of nanomedicine due to their unique properties. This review offers a comprehensive overview of NDs synthesis methods, properties, and their uses in biomedical applications. Various synthesis techniques, such as detonation, high-pressure, high-temperature, and chemical vapor deposition, offer distinct advantages in tailoring NDs' size, shape, and surface properties. Surface modification methods further enhance NDs' biocompatibility and enable the attachment of bioactive molecules, expanding their applicability in biological systems. NDs serve as promising nanocarriers for drug delivery, showcasing biocompatibility and the ability to encapsulate therapeutic agents for targeted delivery. Additionally, NDs demonstrate potential in cancer treatment through hyperthermic therapy and vaccine enhancement for improved immune responses. Functionalization of NDs facilitates their utilization in biosensors for sensitive biomolecule detection, aiding in precise diagnostics and rapid detection of infectious diseases. This review underscores the multifaceted role of NDs in advancing biomedical applications. By synthesizing NDs through various methods and modifying their surfaces, researchers can tailor their properties for specific biomedical needs. The ability of NDs to serve as efficient drug delivery vehicles holds promise for targeted therapy, while their applications in hyperthermic therapy and vaccine enhancement offer innovative approaches to cancer treatment and immunization. Furthermore, the integration of NDs into biosensors enhances diagnostic capabilities, enabling rapid and sensitive detection of biomolecules and infectious diseases. Overall, the diverse functionalities of NDs underscore their potential as valuable tools in nanomedicine, paving the way for advancements in healthcare and biotechnology.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:24

Enthalten in:

Chemical record (New York, N.Y.) - 24(2024), 4 vom: 16. Apr., Seite e202400006

Sprache:

Englisch

Beteiligte Personen:

Hyder, Ali [VerfasserIn]
Ali, Akbar [VerfasserIn]
Buledi, Jamil A [VerfasserIn]
Memon, Ayaz Ali [VerfasserIn]
Iqbal, Muzaffar [VerfasserIn]
Bangalni, Talib Hussain [VerfasserIn]
Solangi, Amber R [VerfasserIn]
Thebo, Khalid Hussain [VerfasserIn]
Akhtar, Javeed [VerfasserIn]

Links:

Volltext

Themen:

Biosensing
Diamond core
Drug delivery
Functionalization
Journal Article
Nanodiamonds
Review
Vaccines

Anmerkungen:

Date Completed 16.04.2024

Date Revised 16.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/tcr.202400006

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM370196023