The roles of templates consisting of amino acids in the synthesis and application of gold nanoclusters

Gold nanoclusters (AuNCs) with low toxicity, high photostability, and facile synthesis have attracted great attention. The ligand is of great significance in stabilizing AuNCs and regulating their properties. Ligands consisting of amino acids (proteins and peptides) are an ideal template for synthesizing applicative AuNCs due to their inherent bioactivity, biocompatibility, and accessibility. In this review, we summarize the correlation of the template consisting of amino acids with the properties of AuNCs by analyzing different peptide sequences. The selection of amino acids can regulate the fluorescence excitation/emission and intensity, size, cell uptake, and light absorption. By analyzing the role played by AuNCs stabilized by proteins and peptides in the application, universal rules and detailed performances of sensors, antibacterial agents, therapeutic reagents, and light absorbers are reviewed. This review can guide the template design and application of AuNCs when selecting proteins and peptides as ligands.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:16

Enthalten in:

Nanoscale - 16(2024), 15 vom: 18. Apr., Seite 7287-7306

Sprache:

Englisch

Beteiligte Personen:

Ma, Jinliang [VerfasserIn]
Yang, Mengmeng [VerfasserIn]
Zhang, Bin [VerfasserIn]
Niu, Mingfu [VerfasserIn]

Links:

Volltext

Themen:

7440-57-5
Amino Acids
Gold
Journal Article
Peptides
Proteins
Review

Anmerkungen:

Date Completed 19.04.2024

Date Revised 19.04.2024

published: Electronic

Citation Status MEDLINE

doi:

10.1039/d3nr06042j

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM37019375X