Development of non-invasive flexible directional microwave ablation for central lung cancer : a simulation study
© 2024 Institute of Physics and Engineering in Medicine..
Transbronchial microwave ablation (MWA) with flexible antennas has gradually become an attractive alternative to percutaneous MWA for lung cancer due to its characteristic of non-invasiveness. However, flexible antennas for the precision ablation of lung tumors that are adjacent to critical bronchial structures are still not available. In this study, a non-invasive flexible directional (FD) antenna for early stage central lung tumors surrounding the bronchia was proposed. A comprehensive numerical MWA model with the FD antenna was developed in a real human-sized left lung model. The structure of the antenna and the treatment protocol were optimized by a generic algorithm for the precision ablation of two cases of early stage central lung cancer (i.e. spherical-like and ellipsoidal tumors). The electromagnetic efficiency of the optimized antenna was also improved by implementing an optimizedπ-matching network for impedance matching. The results indicate that the electromagnetic energy of MWA can be restricted to a particular area for precision ablation of specific lung tumors using the FD antenna. This study contributes to the field of lung cancer management with MWA.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2024 |
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Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:69 |
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Enthalten in: |
Physics in medicine and biology - 69(2024), 9 vom: 22. Apr. |
Sprache: |
Englisch |
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Beteiligte Personen: |
Fang, Zheng [VerfasserIn] |
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Links: |
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Themen: |
Flexible directional antenna |
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Anmerkungen: |
Date Completed 23.04.2024 Date Revised 24.04.2024 published: Electronic Citation Status MEDLINE |
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doi: |
10.1088/1361-6560/ad3795 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM370169263 |
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520 | |a Transbronchial microwave ablation (MWA) with flexible antennas has gradually become an attractive alternative to percutaneous MWA for lung cancer due to its characteristic of non-invasiveness. However, flexible antennas for the precision ablation of lung tumors that are adjacent to critical bronchial structures are still not available. In this study, a non-invasive flexible directional (FD) antenna for early stage central lung tumors surrounding the bronchia was proposed. A comprehensive numerical MWA model with the FD antenna was developed in a real human-sized left lung model. The structure of the antenna and the treatment protocol were optimized by a generic algorithm for the precision ablation of two cases of early stage central lung cancer (i.e. spherical-like and ellipsoidal tumors). The electromagnetic efficiency of the optimized antenna was also improved by implementing an optimizedπ-matching network for impedance matching. The results indicate that the electromagnetic energy of MWA can be restricted to a particular area for precision ablation of specific lung tumors using the FD antenna. This study contributes to the field of lung cancer management with MWA | ||
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700 | 1 | |a Hong, Xiaowu |e verfasserin |4 aut | |
700 | 1 | |a Moser, Michael A J |e verfasserin |4 aut | |
700 | 1 | |a Zhang, Wenjun |e verfasserin |4 aut | |
700 | 1 | |a Zhang, Bing |e verfasserin |4 aut | |
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